Skip to main content

Table 2 Comparison of the parametric characteristics of women with unexplained elevations of MSAFP according to those with and without complications of pregnancy

From: The C677T methylenetetrahydrofolate reductase variant and third trimester obstetrical complications in women with unexplained elevations of maternal serum alpha-fetoprotein

Characteristic Mean Cases (SD) Mean Controls (SD) p value
MSAFP result 2.78 (± 0.62) 3.16 (± 3.76) 0.398
weeks gestation 17.1 (± 1.61) 16.9 (± 1.40) 0.432
μg/folate/day in pregnancy2 1216 (± 915) 1010 (± 892) 0.206
μg/folate/day at time of study2 557 (± 341) 523 (± 498) 0.588
erc folate (nmol/L RBC) 1234 (± 289) 1208 (± 317) 0.632
serum folate (nmol/L) 32.3 (± 5.80) 32.3 (± 5.71) 0.956
serum homocysteine (μmol/L) 7.8 (± 2.26) 8.4 (± 2.80) 0.246
μg B12/day in pregnancy2 12.4 (± 5.37) 13.4 (8.31) 0.488
μg B12/day at time of study2 8.9 (± 12.26) 8.6 (± 10.83) 0.899
mg B6/day in pregnancy2 8.4 (± 9.69) 7.2 (± 9.01) 0.461
mg B6/day at time of study2 6.0 (± 13.35) 5.5 (± 11.10) 0.792
mother's age at delivery 31 (± 4.19) 30 (± 5.19) 0.251
mother's weight in Kg 76 (± 17.26) 69 (± 16.09) 0.0131
  1. 1 This value is not significant after Bonferroni correction for multiple comparisons. See discussion. 2Data was skewed due to a small number of women in both groups taking large dose vitamin supplements. When these women were removed from the analysis the result remained nonsignificant.