Characteristic
|
Mean Cases (SD)
|
Mean Controls (SD)
|
p value
|
---|
MSAFP result
|
2.78 (± 0.62)
|
3.16 (± 3.76)
|
0.398
|
weeks gestation
|
17.1 (± 1.61)
|
16.9 (± 1.40)
|
0.432
|
μg/folate/day in pregnancy2
|
1216 (± 915)
|
1010 (± 892)
|
0.206
|
μg/folate/day at time of study2
|
557 (± 341)
|
523 (± 498)
|
0.588
|
erc folate (nmol/L RBC)
|
1234 (± 289)
|
1208 (± 317)
|
0.632
|
serum folate (nmol/L)
|
32.3 (± 5.80)
|
32.3 (± 5.71)
|
0.956
|
serum homocysteine (μmol/L)
|
7.8 (± 2.26)
|
8.4 (± 2.80)
|
0.246
|
μg B12/day in pregnancy2
|
12.4 (± 5.37)
|
13.4 (8.31)
|
0.488
|
μg B12/day at time of study2
|
8.9 (± 12.26)
|
8.6 (± 10.83)
|
0.899
|
mg B6/day in pregnancy2
|
8.4 (± 9.69)
|
7.2 (± 9.01)
|
0.461
|
mg B6/day at time of study2
|
6.0 (± 13.35)
|
5.5 (± 11.10)
|
0.792
|
mother's age at delivery
|
31 (± 4.19)
|
30 (± 5.19)
|
0.251
|
mother's weight in Kg
|
76 (± 17.26)
|
69 (± 16.09)
|
0.0131
|
- 1 This value is not significant after Bonferroni correction for multiple comparisons. See discussion. 2Data was skewed due to a small number of women in both groups taking large dose vitamin supplements. When these women were removed from the analysis the result remained nonsignificant.