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Table 2 Comparison of the parametric characteristics of women with unexplained elevations of MSAFP according to those with and without complications of pregnancy

From: The C677T methylenetetrahydrofolate reductase variant and third trimester obstetrical complications in women with unexplained elevations of maternal serum alpha-fetoprotein

Characteristic

Mean Cases (SD)

Mean Controls (SD)

p value

MSAFP result

2.78 (± 0.62)

3.16 (± 3.76)

0.398

weeks gestation

17.1 (± 1.61)

16.9 (± 1.40)

0.432

μg/folate/day in pregnancy2

1216 (± 915)

1010 (± 892)

0.206

μg/folate/day at time of study2

557 (± 341)

523 (± 498)

0.588

erc folate (nmol/L RBC)

1234 (± 289)

1208 (± 317)

0.632

serum folate (nmol/L)

32.3 (± 5.80)

32.3 (± 5.71)

0.956

serum homocysteine (μmol/L)

7.8 (± 2.26)

8.4 (± 2.80)

0.246

μg B12/day in pregnancy2

12.4 (± 5.37)

13.4 (8.31)

0.488

μg B12/day at time of study2

8.9 (± 12.26)

8.6 (± 10.83)

0.899

mg B6/day in pregnancy2

8.4 (± 9.69)

7.2 (± 9.01)

0.461

mg B6/day at time of study2

6.0 (± 13.35)

5.5 (± 11.10)

0.792

mother's age at delivery

31 (± 4.19)

30 (± 5.19)

0.251

mother's weight in Kg

76 (± 17.26)

69 (± 16.09)

0.0131

  1. 1 This value is not significant after Bonferroni correction for multiple comparisons. See discussion. 2Data was skewed due to a small number of women in both groups taking large dose vitamin supplements. When these women were removed from the analysis the result remained nonsignificant.