Figure 3

Histologic sections of ovaries. Ovaries were removed from rhesus monkeys after 90 days of treatment with GnRH antagonist prior to (left panel) and following administration of r-hFSH and r-hLH (right panel). Note the absence of any large (>1 mm diameter) antral follicles following GnRH antagonist exposure, versus the development of 2–6 mm antral follicles after 9 days of gonadotropin treatment. See text, and ref [39] for further details.