Changes in extracellular matrix (ECM) and ECM-associated proteins in the metastatic progression of prostate cancer

Table 1 Basic Properties of Prostate Cell Lines.

Cell Line	Origin	Androgen Responsiveness	Tumorigenicity
NbE1.4 [151–154]	Normal rat ventral prostate	Androgen sensitive	None
P69 [148, 149]	Normal Human prostate	Androgen independent	Very poor
DU-145 [147]	Human brain metastasis	Androgen independent	High
LNCaP [145]	Human lymph node metastasis	Androgen sensitive	Low
C4-2* [113, 144]	Human castrated mice	Androgen refractory	High with bone metastases
VCaP [150]	Human bone metastasis	Androgen sensitive	High
PC-3 [146]	Human bone metastasis	Androgen independent	High

*This cell line was derived from the original co-inoculation of LNCaP and bone stromal cells in mice. References for each cell line are as follows: LNCaP (Lymph Node Carcinoma of the Prostate), PC-3 (Prostate Cancer-3), DU-145 (Dura-145), and VCaP (Vertebral-Cancer of the Prostate).

ISSN: 1477-7827