Table 4 Longitudinal analysis: percent change (95% CIs) in thyroid and sex hormone concentrations in relation to interquartile range increase in urinary phthalate metabolite concentration
Analyte | % Change (95% CI) | p-value | % Change (95% CI) | p-value | % Change (95% CI) | p-value |
|---|---|---|---|---|---|---|
|  | Free T3 (n = 181 observations) | Free T4 (n = 181 observations) | ln-TSH (n = 181 observations) | |||
MBzP | 0.18 (-3.42, 3.77) | 0.92 | 0.58 (-4.45, 5.56) | 0.82 | 5.51 (-4.40, 16.5) | 0.28 |
MBP | 1.33 (-1.90, 4.67) | 0.42 | 0.63 (-4.00, 5.21) | 0.79 | 3.28 (-5.58, 12.8) | 0.48 |
MiBP | 0.19 (-2.86, 3.14) | 0.90 | 1.14 (-3.06, 5.42) | 0.59 | 4.64 (-3.73, 13.0) | 0.28 |
MEP | 1.11 (-2.74, 4.96) | 0.57 | 2.68 (-2.68, 7.83) | 0.33 | 0.05 (-10.1, 11.3) | 0.99 |
MCPP | -2.89 (-5.65, -0.02) | 0.049* | -2.01 (-6.12, 2.10) | 0.34 | 1.60 (-6.05, 9.88) | 0.68 |
MCOP | -2.03 (-5.08, 0.98) | 0.18 | -1.11 (-5.26, 3.13) | 0.61 | -2.52 (-10.3, 6.13) | 0.56 |
MCNP | 0.48 (-2.03, 2.94) | 0.71 | -1.64 (-5.28, 1.93) | 0.36 | 3.50 (-2.98, 10.4) | 0.30 |
ΣDEHP | -0.28 (-3.63, 0.30) | 0.87 | -0.93 (-5.56, 3.79) | 0.70 | 7.21 (-1.87, 16.6) | 0.12 |
|  | Estradiol (n = 175 observations) | SHBG (n = 147 observations) | ln-progesterone (n = 179 observations) | |||
MBzP | 0.86 (-8.52, 10.3) | 0.86 | 4.89 (-1.52, 11.3) | 0.13 | 3.16 (-4.56, 11.5) | 0.67 |
MBP | 2.65 (-5.90, 11.2) | 0.54 | -0.65 (-6.29, 4.98) | 0.82 | 3.71 (-3.44, 11.2) | 0.31 |
MiBP | 1.56 (-6.27, 9.39) | 0.69 | 1.19 (-4.25, 6.61) | 0.66 | 2.48 (-3.96, 9.49) | 0.46 |
MEP | 1.60 (-8.49, 11.7) | 0.75 | -2.24 (-9.43, 4.97) | 0.54 | -10.6 (-17.6, -2.84) | 0.01* |
MCPP | -3.86 (-11.5, 3.80) | 0.32 | -1.27 (-6.40, 3.86) | 0.62 | -4.31 (-10.2, 1.98) | 0.17 |
MCOP | -3.59 (-11.4, 4.24) | 0.36 | -0.93 (-6.44, 4.58) | 0.74 | -4.83 (-11.0, 1.57) | 0.13 |
MCNP | -2.03 (-8.50, 4.41) | 0.53 | -0.66 (-4.85, 3.46) | 0.75 | -2.06 (-7.22, 3.28) | 0.43 |
ΣDEHP | -0.56 (-9.17, 8.06) | 0.90 | -4.11 (-9.83, 1.62) | 0.16 | 1.79 (-5.17, 9.39) | 0.62 |