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Table 4 Genes whose transcript level was up-regulated in Group A (n = 5) when compared with Group B (n = 6) and Group C (n = 6) in the microarray analyses

From: Endometrial gene expression reveals compromised progesterone signaling in women refractory to embryo implantation

UniGene ID

Gene symbol

Gene title

A vs. B

p value

A vs. C

p value

Average

Hs.35086

USP1

Ubiquitin specific protease 1 (USP1), mRNA.

42.52

0.00022

44.32

0.00043

43.42

Hs.436977

SYTL3

Synaptotagmin-like 3

20.68

0.00043

26.72

0.00013

23.70

Hs.133421

LIFR

Leukemia inhibitory factor receptor

43.71

0.00086

3.32

0.00022

23.52

Hs.160211

THRAP3

Thyroid hormone receptor associated protein 3 (THRAP3), mRNA.

29.04

0.00013

3.66

0.00043

16.35

Hs.532399

ZC3H11A

KIAA0663 gene product (KIAA0663), mRNA.

4.38

0.00043

28.05

0.00086

16.21

Hs.652169

PLGLB2

Plasminogen-like B2

21.71

0.00086

9.45

0.00086

15.58

Hs.524809

CLIP1

Restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) (RSN), transcript variant 2, mRNA.

2.19

0.00043

25.81

0.00043

14.00

Hs.16355

MYH10

Myosin, heavy polypeptide 10, non-muscle (MYH10), mRNA.

2.6

0.00013

24.08

0.00022

13.34

Hs.502829

SF1

Splicing factor 1 (SF1), transcript variant 4, mRNA.

21.86

0.00043

4.08

0.00086

12.97

Hs.517949

MAP4

Microtubule-associated protein 4 (MAP4), transcript variant 1, mRNA.

10.41

0.00043

11.96

0.00013

11.18

Hs.8118

SMCHD1

KIAA0650 protein

18.77

0.00013

2.17

0.00043

10.47

Hs.514806

GALNT1

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (GALNT1), mRNA.

11

0.00043

9.38

0.00043

10.19

Hs.130293

LUC7L3

Cisplatin resistance-associated overexpressed protein (CROP), transcript variant 2, mRNA.

6.32

0.00043

11.88

0.00022

9.10

Hs.143728

WASL

Wiskott-Aldrich syndrome-like (WASL), mRNA.

2.07

0.00022

14.32

0.00086

8.20

Hs.532082

IL6ST

Interleukin 6 signal transducer (gp130, oncostatin M receptor) (IL6ST), transcript variant 2, mRNA.

2.95

0.00013

13

0.00043

7.97

Hs.2913

EPHB3

EphB3 = HEK2 = tyrosine kinase receptor = large erk kinase

11.39

0.00086

4.41

0.00086

7.90

Hs.431081

USP53

Ubiquitin specific protease 53

2.23

0.00013

13.55

0.00043

7.89

Hs.194726

BAG4

BCL2-associated athanogene 4 (BAG4), mRNA.

11.71

0.00013

3.16

0.00086

7.44

Hs.464971

PIK3C3

Phosphoinositide-3-kinase, class 3

3.92

0.00043

10.41

0.00086

7.16

Hs.9997

SECISBP2L

KIAA0256 gene product (KIAA0256), mRNA.

5.43

0.00086

7.36

0.00013

6.39

Hs.497788

EPRS

Glutamyl-prolyl-tRNA synthetase (EPRS), mRNA.

4.41

0.00043

8.11

0.00043

6.26

Hs.101014

CEP57

Translokin (KIAA0092), mRNA.

5.03

0.00086

7.31

0.00086

6.17

Hs.143600

GOLIM4

Golgi phosphoprotein 4 (GOLPH4), mRNA.

2.46

0.00043

9.85

0.00022

6.16

Hs.24485

SMC3

Chondroitin sulfate proteoglycan 6 (bamacan) (CSPG6), mRNA.

2.53

0.00022

9.65

0.00043

6.09

Hs.193832

GPATCH4

G patch domain containing 4 (GPATC4), transcript variant 3, mRNA.

3.32

0.00013

7.94

0.00086

5.63

Hs.406695

PRDM7

PR domain containing 7 (PRDM7), mRNA.

2.04

0.00086

8.46

0.00086

5.25

Hs.42194

SPCS3

Signal peptidase complex subunit 3 homolog (S. cerevisiae) (SPCS3), mRNA.

2.1

0.00043

8.34

0.00022

5.22

Hs.458418

KIAA1731

PREDICTED: KIAA1731 protein (KIAA1731), mRNA.

2.04

0.00013

8.4

0.00086

5.22

Hs.49853

CCAR1

Cell division cycle and apoptosis regulator 1

2.75

0.00086

7.67

0.00013

5.21

Hs.496414

ATP7A

ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)

2.89

0.00086

7.16

0.00043

5.02

Hs.481181

NEK1

NIMA (never in mitosis gene a)-related kinase 1 (NEK1), mRNA.

3.07

0.00086

5.35

0.00043

4.21

Hs.440833

PKN2

protein kinase N2 (PKN2), mRNA.

6.02

0.00022

2.14

0.00043

4.08

Hs.524009

AASDHPPT

Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

3.89

0.00013

4.2

0.00086

4.04

Hs.26904

SEC63

SEC63 homolog (S. cerevisiae)

2.95

0.00086

3.78

0.00043

3.37

Hs.93485

SCN2A

MRNA; cDNA DKFZp761D191 (from clone DKFZp761D191)

2.08

0.00043

4.5

0.00013

3.29

Hs.31082

TMEM33

Transmembrane protein 33

2.19

0.00086

4.35

0.00043

3.27

Hs.371372

CWC27

Serologically defined colon cancer antigen 10 (SDCCAG10), mRNA.

2.95

0.00043

3.51

0.00086

3.23

Hs.523299

EIF3A

Eukaryotic translation initiation factor 3, subunit 10 theta, 150/170 kDa (EIF3S10), mRNA.

2.68

0.00022

3.58

0.00022

3.13

Hs.440320

CUL5

Cullin 5 (CUL5), mRNA.

2.6

0.00043

3.25

0.00043

2.93

Hs.203965

PHTF2

Putative homeodomain transcription factor 2

3.56

0.00013

2.3

0.00086

2.93

Hs.335068

TGS1

Nuclear receptor coactivator 6 interacting protein (NCOA6IP), mRNA.

3.63

0.00086

2.16

0.00013

2.89

Hs.189075

TWF1

Twinfilin, actin-binding protein, homolog 1 (Drosophila)

2.36

0.00086

2.97

0.00043

2.67

Hs.127310

UHMK1

U2AF homology motif (UHM) kinase 1 (UHMK1), mRNA.

2.85

0.00086

2.46

0.00043

2.66

Hs.430849

OSBPL8

Oxysterol binding protein-like 8 (OSBPL8), transcript variant 1, mRNA.

2.03

0.00022

3.05

0.00022

2.54

Hs.150557

KLF9

Basic transcription element binding protein 1 (BTEB1), mRNA.

2.6

0.00086

2.39

0.00043

2.50

Hs.210850

HECTD1

HECT domain containing 1 (HECTD1), mRNA.

2.35

0.00013

2.6

0.00086

2.47

Hs.142442

HP1BP3

Heterochromatin protein 1, binding protein 3

2.08

0.00086

2.41

0.00013

2.25

Hs.369284

ESF1

Chromosome 20 open reading frame 6 (C20orf6), mRNA.

2.13

0.00013

2.3

0.00086

2.21

Hs.119023

SMC2

SMC2 structural maintenance of chromosomes 2-like 1 (yeast) (SMC2L1), mRNA.

2.25

0.00022

2

0.00022

2.13

Hs.481927

NIPBL

Nipped-B homolog (Drosophila)

2.11

0.00043

2.04

0.00086

2.08

Hs.374201

KIF21A

kinesin family member 21A (KIF21A), mRNA.

2.13

0.00013

2

0.00013

2.06

  1. Data includes genes with increased transcript levels displaying a ≥2-fold difference in average A vs. B and A vs. C.