Polymorphisms in estrogen receptors predict the risk of male infertility: a meta-analysis

Table 3 Stratification analyses of genetic susceptibility of rs9340799 polymorphism to male infertility

Category	Cases/controls	AA vs. GG			GA vs. GG			AA + GA vs. GG			AA vs. GA + GG			A allele vs. G allele
		OR(95% CI)	P ^a	I ²	OR(95% CI)	P ^a	I ²	OR(95% CI)	P ^a	I ²	OR(95% CI)	P ^a	I ²	OR(95% CI)	P ^a	I ²
Total	774/841	1.67(1.21-2.32)	0.392	3.9	1.03(0.76-1.39)	0.764	0	1.27(0.96-1.68)	0.796	0	1.63(1.32-2.03)	0.077	49.7	1.39(1.13-1.68)	0.172	35.3
*RACE*
Asian	368/416	1.56(0.93-2.62)	0.714	0	0.81(0.49-1.34)	0.524	0	1.13(0.71-1.82)	0.952	0	1.93(1.42-2.62)	0.768	0	1.49(1.18-1.86)	0.375	0
Caucasian	406/425	1.75(1.15-2.68)	0.174	39.7	1.17(0.81-1.71)	0.847	0	1.35(0.95-1.92)	0.569	0	1.38(1.02-1.88)	0.062	59.2	1.39(0.97-1.81)	0.109	50.5

^aP value of Q-test for heterogeneity test.
I²: 0–25, no heterogeneity; 25–50, modest heterogeneity; 50, high heterogeneity.
Bold numbers mean statistically significant results.

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