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Table 2 Stratification analyses of genetic susceptibility of rs2234693 polymorphism to male infertility

From: Polymorphisms in estrogen receptors predict the risk of male infertility: a meta-analysis

Category

Cases/controls

CC vs. TT

CT vs. TT

CC + CT vs. TT

CC vs. CT + TT

C allele vs. T allele

  

OR(95% CI)

P a

I 2

OR(95% CI)

P a

I 2

OR(95% CI)

P a

I 2

OR(95% CI)

P a

I 2

OR(95% CI)

P a

I 2

Total

774/841

0.72(0.54-0.96)

0.282

20.1

0.74(0.58-0.94)

0.533

0

0.73(0.58-0.91)

0.368

7.5

0.90(0.71-1.13)

0.465

0

0.84(0.71-1.01)

0.190

32.8

RACE

                

Asian

368/416

0.61(0.40-0.93)

0.670

0

0.67(0.49-0.93)

0.358

0

0.66(0.49-0.89)

0.593

0

0.83(0.58-1.18)

0.257

22.1

0.78(0.64-0.96)

0.681

0

Caucasian

406/425

0.83(0.46-1.23)

0.175

39.5

0.83(0.57-1.19)

0.460

0

0.81(0.58-1.14)

0.232

30

0.95(0.70-1.29)

0.395

0

0.87(0.64-1.18)

0.103

51.5

  1. I2: 0–25, no heterogeneity; 25–50, modest.
  2. aP value of Q-test for heterogeneity test.
  3. Bold numbers mean statistically significant results.