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Table 3 Gel spots used in PCA and protein identities

From: A proteomic analysis of the endometrium in obese and overweight women with recurrent miscarriage: preliminary evidence for an endometrial defect

Spot number

Fold change

Direction of change

ANOVA (p)

Protein identification

Mascot score

 

Recurrent miscarriage versus control – All subjects

1163

2.3

<

0.547

Haptoglobin alpha chain

109

1172

2.2

<

0.547

Haptoglobin alpha chain

*

868

1.8

>

0.547

  

254

1.8

>

0.547

Transferrin

547

252

1.8

>

0.547

Transferrin

693

1183

1.6

<

0.547

Haptoglobin alpha chain

*

119

1.6

>

0.547

Serum albumin

162

635

1.6

<

0.547

Haptoglobin beta chain

160

3

1.5

<

0.547

α-1-Antitrypsin

684

489

1.5

>

0.547

  
 

Recurrent miscarriage versus control – Obese only

263

5.3

>

0.004

  

1172

2.5

<

0.017

Haptoglobin alpha chain

 

620

1.9

<

0.025

  

1163

2.0

<

0.036

Haptoglobin alpha chain

160

152

1.8

>

0.037

  
 

Recurrent miscarriage versus control – Lean only

1163

4.1

<

0.026

Haptoglobin alpha chain

109

901

2.7

>

0.014

  

1183

2.2

<

0.036

Haptoglobin alpha chain

*

83

2.0

<

0.030

  

252

2.0

>

0.007

Transferrin

693

601

1.9

<

0.048

Hemoglobin beta subunit

522

856

1.9

<

0.020

Hemoglobin beta subunit

167

91

1.6

<

0.049

  

561

1.6

<

0.002

  

401

1.6

>

0.039

  

800

1.6

<

0.020

  

184

1.5

>

0.016

  

125

1.5

<

0.039

  

937

1.5

>

0.023

  

659

1.5

<

0.038

  

887

1.5

>

0.006

  

760

1.4

>

0.019

  

1009

1.3

>

0.039

  
 

Obese versus lean – Recurrent miscarriage only

1163

2.0

>

0.014

Haptoglobin alpha chain

109

1044

1.8

<

0.010

  

930

1.6

>

0.037

  

1301

1.5

>

0.040

Transthyretin (Prealbumin)

158

601

1.5

>

0.045

Hemoglobin beta subunit

522

  1. *Identity inferred from position in 2D gel indicating the same molecular weight and nearly the same isoelectric point as spot 1163.