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Figure 3 | Reproductive Biology and Endocrinology

Figure 3

From: Regulation of ACVR1 and ID2 by cell-secreted exosomes during follicle maturation in the mare

Figure 3

Exosomal miRNAs predicted to regulate ACVR1 and ID2 transcripts. (A) MiR-27b predicted binding sites in the 3’UTR of equine ACVR1 and ID2, and miR-372 and miR-382 predicted binding sites in the 3’UTR of equine ACVR1. (B) Relative levels of miR-27b, miR-372, and miR-382 in exosomes isolated from follicular fluid of mid-estrous and pre-ovulatory follicles that are predicted to target ACVR1 and/or ID2. Values on y-axis indicate 1/normalized (Δ) Ct values relative to geometric mean of ACTB and GAPDH or miR-99b and protein ratio. * = P < 0.05 between follicular stage.

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