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Figure 2 | Reproductive Biology and Endocrinology

Figure 2

From: Use of antagonists and morpholinos in loss-of-function analyses: estrogen receptor ESR2a mediates the effects of 17alpha-ethinylestradiol on primordial germ cell distribution in zebrafish

Figure 2

Percentage of zebrafish embryos with ectopic PGCs in different exposure groups. In the control, 1 ng/L, 10 ng/L, and 100 ng/L EE2 exposure groups, less than 2% of the zebrafish embryos showed ectopic PGCs. In the 500 ng/L EE2 exposure group, approximately 13% of zebrafish embryos contained ectopic PGCs. In the 1 μg/L EE2 exposure group, approximately 20% of zebrafish embryos contained ectopic PGCs. In the 2 μg/L EE2 exposure group, approximately 19% of zebrafish embryos contained ectopic PGCs. These rates were significantly higher than that of other groups (p < 0.01, one-way ANOVA followed by Tukey’s test).

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