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Table 3 Comparison of patients with thyroid medication for TSH levels exceeding the threshold of 2.5 μIU/ml and patients without any thyroid medication

From: The impact of thyroid function on intrauterine insemination outcome - a retrospective analysis

  Thyroid medication for TSH levels No thyroid medication Thyroid medication for overt hypothyroidism pd pe
  > 2.5 μIU/ml (n = 71) (n = 372) (n = 97)   
Age (years) a 33 (27-40) 33 (28-39) 34 (30-39) 0.324 0.047 c
Body mass index (kg/m 2 ) a 22.3 (19.4-25.1) 22.9 (20.3-26.7) 23.1 (21.4—25.1) 0.260 0.340
Primary infertility (vs. secondary infertility) b 36 (50.7) 202 (54.3) 39 (40.2) 0.578 0.176
Parity b 0 (0-1) 0 (0-1) 0 (0-1) 0.961 0.667
TSH (μIU/ml) a 1.6 (1.1-2.2) 1.5 (1.1-2.0) 1.4 (0.4-2.2) 0.422 0.107
TPO-Ab > upper level of normal b 8 (11.3) 14 (3.8) 39 (40.2) 0.014 c < 0.001 c
TG-Ab > upper level of normal b 22 (31.0) 57 (15.3) 28 (28.9) 0.004 c 0.767
Presence of PCO-S b 16 (22.5) 56 (15.1) 17 (17.5) < 0.001 c 0.419
Metformin treatment b 5 (7.0) 19 (5.1) 10 (10.3) 0.565 0.588
Clomifen citrate stimulation b 23 (32.4) 115 (30.9) 27 (27.8) 0.805 0.523
Number of IUI treatment cycle a 1 (1-1) 1 (1-1) 1 (1-1) 0.063 0.598
Ovulation induction with HCG b 36 (50.7) 181 (48.7) 49 (50.5) 0.752 0.981
Endometrial thickness a 9 (8-10) 9 (8-10) 9 (8-10) 0.866 0.864
Male factor b 35 (49.3) 195 (52.4) 52 (53.6) 0.629 0.581
Pregnancy rate b 16 (23.9) 19 (5.1) 2 (2.1) < 0.001 c < 0.001 c
  1. Patients with overt hypothyroidism were excluded for this analysis.
  2. aContinuous variable, provided in median (interquartile range).
  3. bNominal variable, provided in n (%).
  4. cItalic letters indicate statistical significance.
  5. dComparison of patients with thyroid medication for TSH levels > 2.5 μIU/ml and patients without thyroid medication.
  6. eComparison of patients with thyroid medication for TSH levels > 2.5 μIU/ml and patients with thyroid medication for overt hypothyroidism.