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Table 2 Univariate and multivariate analysis

From: The impact of thyroid function on intrauterine insemination outcome - a retrospective analysis

  Pregnancy (N = 37) No pregnancy (N = 503) Univariate analysis Multivariate analysis
    OR (95% CI)a p OR (95% CI)a p
Age (years)b 30 (30-35) 34 (29-39) 0.92 (0.87;0.98) 0.015 d 0.94 (0.87;0.99) 0.049 d
Body mass index (kg/m 2 ) b 20.9 (19.9-27.0) 22.9 (20.4-26.0) 1.02 (0.93;1.07) 0.931 - -
Primary infertility (vs. secondary infertility) c 19 (51.4) 258 (51.3) 1.00 (0.95;1.05) 0.861 - -
Parity c 0 (0-1) 0 (0-0) 1.01 (0.60;1.71) 0.954 - -
TSH (μIU/ml) b 1.6 (1.1-2.2) 1.9 (1.2-2.4) 0.89 (0.46;1.21) 0.556 - -
TPO-Ab > upper level of normal c 0 (0) 61 (12.1) 0.07 (0.05;0.10) 0.015 d 0 (0;inf) 0.997
TG-Ab > upper level of normal c 2 (5.4) 105 (20.9) 0.22 (0.05;0.91) 0.037 d 0.87 (0.19;4.03) 0.861
Thyroid medication for overt hypothyroidism c 2 (5.4) 95 (18.9) 0.25 (0.06;1.04) 0.036 d 0.54 (0.12;2.47) 0.338
Thyroid medication TSH > 2.5 μIU/ml c 16 (43.2) 55 (10.9) 6.94 (3.60;13.40) <0.001 d 3.31 (1.31;8.35) 0.009 d
Presence of PCO-S c 8 (21.6) 81 (16.1) 0.71 (0.31;1.60) 0.407 - -
Metformin treatment b 3 (8.1) 31 (6.2) 1.34 (0.31;4.92) 0.500 - -
Clomifen citrate stimulation c 19 (51.4) 146 (29.0) 0.39 (0.20;0.77) 0.006 d 0.77 (0.32;1.85) 0.629
Number of IUI treatment cycle b 1 (1-1) 1 (1-1) 0.90 (0.59;1.37) 0.638 - -
Ovulation induction with HCG c 27 (73.0) 239 (47.5) 2.95 (1.40;6.22) 0.005 d 5.37 (1.72;16.69) 0.004 d
Endometrial thickness b 10 (8-11) 8 (9-10) 1.09 (0.91;1.31) 0.324 - -
Male factor c 13 (35.1) 269 (53.5) 0.47 (0.23;0.95) 0.034 d 0.60 (0.27;1.03) 0.067
  1. aOR = odds ratio, 95% CI = 95% confidence interval.
  2. bContinuous variable, provided in median (interquartile range).
  3. cNominal variable, provided in n (%).
  4. dItalic numbers in p columns indicate statistical significance.