Table 2 Univariate and multivariate analysis
From: The impact of thyroid function on intrauterine insemination outcome - a retrospective analysis
Pregnancy (N = 37) | No pregnancy (N = 503) | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|---|
OR (95% CI)a | p | OR (95% CI)a | p | |||
Age (years)b | 30 (30-35) | 34 (29-39) | 0.92 (0.87;0.98) | 0.015 d | 0.94 (0.87;0.99) | 0.049 d |
Body mass index (kg/m 2 ) b | 20.9 (19.9-27.0) | 22.9 (20.4-26.0) | 1.02 (0.93;1.07) | 0.931 | - | - |
Primary infertility (vs. secondary infertility) c | 19 (51.4) | 258 (51.3) | 1.00 (0.95;1.05) | 0.861 | - | - |
Parity c | 0 (0-1) | 0 (0-0) | 1.01 (0.60;1.71) | 0.954 | - | - |
TSH (μIU/ml) b | 1.6 (1.1-2.2) | 1.9 (1.2-2.4) | 0.89 (0.46;1.21) | 0.556 | - | - |
TPO-Ab > upper level of normal c | 0 (0) | 61 (12.1) | 0.07 (0.05;0.10) | 0.015 d | 0 (0;inf) | 0.997 |
TG-Ab > upper level of normal c | 2 (5.4) | 105 (20.9) | 0.22 (0.05;0.91) | 0.037 d | 0.87 (0.19;4.03) | 0.861 |
Thyroid medication for overt hypothyroidism c | 2 (5.4) | 95 (18.9) | 0.25 (0.06;1.04) | 0.036 d | 0.54 (0.12;2.47) | 0.338 |
Thyroid medication TSH > 2.5 μIU/ml c | 16 (43.2) | 55 (10.9) | 6.94 (3.60;13.40) | <0.001 d | 3.31 (1.31;8.35) | 0.009 d |
Presence of PCO-S c | 8 (21.6) | 81 (16.1) | 0.71 (0.31;1.60) | 0.407 | - | - |
Metformin treatment b | 3 (8.1) | 31 (6.2) | 1.34 (0.31;4.92) | 0.500 | - | - |
Clomifen citrate stimulation c | 19 (51.4) | 146 (29.0) | 0.39 (0.20;0.77) | 0.006 d | 0.77 (0.32;1.85) | 0.629 |
Number of IUI treatment cycle b | 1 (1-1) | 1 (1-1) | 0.90 (0.59;1.37) | 0.638 | - | - |
Ovulation induction with HCG c | 27 (73.0) | 239 (47.5) | 2.95 (1.40;6.22) | 0.005 d | 5.37 (1.72;16.69) | 0.004 d |
Endometrial thickness b | 10 (8-11) | 8 (9-10) | 1.09 (0.91;1.31) | 0.324 | - | - |
Male factor c | 13 (35.1) | 269 (53.5) | 0.47 (0.23;0.95) | 0.034 d | 0.60 (0.27;1.03) | 0.067 |