| Mean difference/RR (95% CI) between r-hFSH plus r-hLH and r-hFSH groups | ||
---|---|---|---|
 | Overall ITT population | Poor responders | Normal responders |
Number of metaphase II oocytes | 0.02 (−0.29 to 0.33)a | 0.69 (0.12 to 1.25)a | −0.28 (−0.66 to 0.10)a |
Number of embryos | 0.09 (−0.11 to 0.30)a | 0.34 (−0.05 to 0.73)a | −0.01 (−0.27 to 0.25)a |
Number of transferred embryos | 0.09 (0.01 to 0.17)a | 0.27 (0.07 to 0.47)a | 0.05 (−0.05 to 0.15)a |
Number of good quality embryos | 0.26 (0.16 to 0.36)a | 0.43 (0.26 to 0.06)a | 0.17 (0.05 to 0.29)a |
Peak oestradiol (ng/L) | 0.24 (0.06 to 0.42)a | 0.21 (−0.12 to 0.54)a | 0.26 (0.03 to 0.48)a |
Duration of ovarian stimulation (days) | −0.23 (−0.50 to 0.05)a | −0.51 (−1.15 to 0.12)a | −0.15 (−0.49 to 0.18)a |
Total r-hFSH dose (IU/1000) | −0.11 (−0.22 to 0.00)a | −0.38 (−0.59 to −0.17)a | −0.06 (−0.16 to 0.04)a |
Biochemical pregnancy rate | 1.25 (1.13 to 1.38)b | 1.38 (1.06 to 1.80)b | 1.22 (1.04 to 1.42)b |
Ongoing pregnancy rate | 1.14 (1.05 to 1.25)b | 1.36 (1.04 to 1.79)b | 1.13 (1.00 to 1.27)b |
Live birth rate | 1.11 (1.01 to 1.21)b | 1.30 (0.95 to 1.78)b | 1.10 (0.94 to 1.29)b |