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Figure 5 | Reproductive Biology and Endocrinology

Figure 5

From: VEGF-D-induced draining lymphatic enlargement and tumor lymphangiogenesis promote lymph node metastasis in a xenograft model of ovarian carcinoma

Figure 5

VEGF-D overexpression upregulates CA125 in the metastatic lymph nodes. (A) Representative sections for CA125 in lymph nodes of mice bearing SKOV3 xenograft- (left panel), SKOV3/pcDNA xenograft (mid panel) or SKOV3/VEGF-D xenografts (right panel). (B) Percentage of CA125-positive area. P < 0.01 vs. mouse bearing SKOV3 or SKOV3/pcDNA xenografts. Each data point represents a single lymph node. Original magnification: ×400; scale bar = 200 μm.

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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