Immunohistochemical expression of MMP-14 and MMP-2, and MMP-2 activity during human ovarian follicular development

Table 2 IHC scores in ovarian follicular development

Histopathological diagnosis	OSE	Primord. Follicle	PF	TF granulosa cells	TF theca cells	CL granulosa cells	Atretic follicle
Teratoma		17+/19*-		++/**	+/*
Simple cyst	++/**						-/-
Serous cystadenoma	++/*					+++/*
Pseudocyst	++/*	2+/9-	+/*
Functional cyst (torsion)	+/*			++/**	+/*
Teratoma (torsion)		4+/6-
Mucinous cystadenoma and Brenner tumour	++/*	2+/1-
Mucinous cystadenoma	+		/-
Normal ovary	+/*	+/*

IHC = ImmunoHistoChemistry, OSE = Ovarian Surface Epithelium, Primord. = Primordial, PF = Primary/Growing Follicle, TF = Tertiary Follicle, CL = Corpus Luteum, - = no MMP-2 or 14 expression, + = MMP-2 expression, * = MMP-14 expression, ++ = moderate MMP-2 expression, ** = moderate MMP-14 expression, +++ = strong MMP-2 expression, the number before the symbols -, + or * indicates the number of follicles found, if no number is indicated, the number is one.

ISSN: 1477-7827