In high responding patients undergoing an initial IVF cycle, elevated estradiol on the day of hCG has no effect on live birth rate

Table 6 Response variables for the entire population and subgroup having good/fair quality embryos transferred on day 3

	Entire population		Good/fair embryos only
Variables	Non-LB	LB	Non-LB	LB
Number	138 (48.3%)	148 (51.7%)*	96 (40.9%)	139 (59.1%)**
Patient age	33.0 ± 4.2^a	31.4 ± 4.0^a	32.9 ± 3.9^d	31.5 ± 3.9^d
FSH dose (IU)	3574 ± 1499^b	3158 ± 1397^b	3423 ± 1490	3124 ± 1381
Estradiol on day of hCG pg/ml	2451 ± 1082	2634 ± 1061	2588 ± 1115	2636 ± 1080
BMI	26.5 ± 6.6	27.1 ± 6.7	27.1 ± 6.4	27.2 ± 6.7
Number retrieved oocytes	15.9 ± 8.2	16.0 ± 6.9	17.2 ± 8.6	16.1 ± 6.8
MII eggs	11.1 ± 6.0	12.1 ± 5.7	12.0 ± 6.2	12.3 ± 5.6
Number of 2PN	6.9 ± 4.1^c	8.1 ± 3.9^c	7.8 ± 4.1	8.1 ± 3.8
Number of embryos transferred	2.19 ± 0.51	2.11 ± 0.29	2.17 ± 0.43	2.11 ± 0.32
AEQS	1.91 ± 0.68^a	1.39 ± 0.49^a	1.54 ± 0.42^a	1.32 ± 0.40^a

All values are Mean ± 1SD.
Differences within row comparing the same response variable by pregnancy status (NLB or LB) for the entire population or patients having only good or fair quality embryos transferred having the same superscript are different; ^ap <0.001; ^bp <0.020; ^cp <0.010, ^dp <0.007.
*Chi Square comparison for difference between Day 3 and Day 5 in the total population for Live Birth was p <0.02.
**Chi Square comparison for difference between Day 3 and Day 5 in population with only good or fair quality embryos used for transfer for Live Birth was NS.

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