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Table 3 Estradiol groups in a subpopulation having good or fair quality embryos for transfer and IVF outcome

From: In high responding patients undergoing an initial IVF cycle, elevated estradiol on the day of hCG has no effect on live birth rate

Variables Group 1 (<2000 pg/mL, n = 95) Group 2 (2000-4000 pg/mL, n = 257) Group 3 > 4000 pg/mL, n = 76) p- value
Age (years) 32.6 ± 4.1 31.4 ± 3.9 30.6 ± 3.9 <0.003
BMI 28.3 ± 7.1 26.2 ± 6.1 24.8 ± 6.1 <0.002
FSH dose (IU)* 3677 ± 1416 2834 ± 1311 1904 ± 901 <0.001
Peak estradiol (pg/mL) 1506 ± 352 2965 ± 564 4763 ± 599 <0.001
Oocytes retrieved 12.5 ± 5.6 20.2 ± 7.4 26.7 ± 8.4 <0.001
MII oocytes 9.6 ± 4.7 15.5 ± 6.3 20.9 ± 7.3 <0.001
Total 2PN 7.0 ± 3.5 10.6 ± 4.7 13.7 ± 5.8 <0.001
AEQS 1.49 ± 0.43 1.43 ± 0.43 1.46 ± 0.42 <0.490
No. embryos transferred 2.11 ± 0.45 2.00 ± 0.35 1.91 ± 0.33 <0.002
BCP (%) 71.6 74.3 78.9 <0.640
CP (%) 62.1 68.5 65.8 <0.550
LB (%) 58.9 63.0 61.8 <0.810
Total pregnancy loss (%) 17.6 15.2 21.7 <0.540
  1. Mean ± 1SD.
  2. Chi-square and ANOVA tests as appropriate. For pregnancy related variables, within row, response variables with different superscripts differ at a minimum of P < 0.05. The number patients in the subpopulation were 428. *The n for FSH dose for the subpopulation was 413 due to missing values.