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Table 3 Estradiol groups in a subpopulation having good or fair quality embryos for transfer and IVF outcome

From: In high responding patients undergoing an initial IVF cycle, elevated estradiol on the day of hCG has no effect on live birth rate

Variables

Group 1 (<2000 pg/mL, n = 95)

Group 2 (2000-4000 pg/mL, n = 257)

Group 3 > 4000 pg/mL, n = 76)

p- value

Age (years)

32.6 ± 4.1

31.4 ± 3.9

30.6 ± 3.9

<0.003

BMI

28.3 ± 7.1

26.2 ± 6.1

24.8 ± 6.1

<0.002

FSH dose (IU)*

3677 ± 1416

2834 ± 1311

1904 ± 901

<0.001

Peak estradiol (pg/mL)

1506 ± 352

2965 ± 564

4763 ± 599

<0.001

Oocytes retrieved

12.5 ± 5.6

20.2 ± 7.4

26.7 ± 8.4

<0.001

MII oocytes

9.6 ± 4.7

15.5 ± 6.3

20.9 ± 7.3

<0.001

Total 2PN

7.0 ± 3.5

10.6 ± 4.7

13.7 ± 5.8

<0.001

AEQS

1.49 ± 0.43

1.43 ± 0.43

1.46 ± 0.42

<0.490

No. embryos transferred

2.11 ± 0.45

2.00 ± 0.35

1.91 ± 0.33

<0.002

BCP (%)

71.6

74.3

78.9

<0.640

CP (%)

62.1

68.5

65.8

<0.550

LB (%)

58.9

63.0

61.8

<0.810

Total pregnancy loss (%)

17.6

15.2

21.7

<0.540

  1. Mean ± 1SD.
  2. Chi-square and ANOVA tests as appropriate. For pregnancy related variables, within row, response variables with different superscripts differ at a minimum of P < 0.05. The number patients in the subpopulation were 428. *The n for FSH dose for the subpopulation was 413 due to missing values.