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Table 2 Estradiol groups in the entire population of patients and IVF outcome

From: In high responding patients undergoing an initial IVF cycle, elevated estradiol on the day of hCG has no effect on live birth rate

Variables Group 1 < 2000 pg/mL, n = 123) Group 2 (2000-4000) pg/ml, n = 288) Group 3 > 4000 pg/mL, n = 78) p- value
Age (years) 32.6 ± 4.2 31.5 ± 4.1 30.6 ± 3.8 <0.003
BMI 27.4 ± 7.0 26.3 ± 6.2 24.9 ± 6.1 <0.024
FSH dose (IU)* 3851 ± 1454 2883 ± 1314 1900 ± 896 <0.001
Peak estradiol (pg/mL) 1489 ± 365 2950.1 ± 561 4758 ± 594 <0.001
Oocytes retrieved 11.9 ± 5.7 19.9 ± 7.5 26.5 ± 8.6 <0.001
MII oocytes 8.9 ± 4.7 15.1 ± 6.3 20.7 ± 7.3 <0.001
Total 2PN 6.4 ± 3.7 10.3 ± 4.7 13.5 ± 5.9 <0.001
AEQS 1.78 ± 0.67 1.57 ± 0.58 1.48 ± 0.44 <0.001
No. embryos transferred 2.11 ± 0.50 2.04 ± 0.40 1.92 ± 0.35 <0.008
BCP (%) 58.5a 70.8b 78.2b <0.007
CP (%) 49.6a 64.2b 65.4b <0.015
LB (%) 47.2 59.0 61.5 0.052
Total pregnancy loss (%) 19.4 16.7 21.3 0.670
Poor quality embryos for transfer (%) 19.5 9.7 1.3 <0.001
  1. Mean ± 1SD.
  2. Chi-square and ANOVA tests as appropriate. For pregnancy related variables, within row, response variables with different superscripts differ at a minimum of P < 0.05. The number patients in the entire population were 489. *The n for FSH dose was 470 due to missing values.