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Figure 1 | Reproductive Biology and Endocrinology

Figure 1

From: Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage

Figure 1

The reconstructed chromosomal status of blastomeres in embryos 1–6 and 8–9. The reconstruction of cell lineage is based on results of aCGH and microsatellite marker analysis. Abnormal blastomeres are shown in pale grey and those with no result are shown in dark grey. The reconstruction assumes 1) anaphase lagging (AL), non-disjunction (ND), selective endoreduplication (ERD) or chromosome breakage cause the observed chromosomal aberrations; 2) a minimal number of the above events that could explain the chromosomal status of the embryos; and 3) one event per cell division as far as possible.

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