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Table 2 Comparison of semen parameters between overall and 4 age groups among varicocele, smokers and alcohol users

From: Infertile men older than 40 years are at higher risk of sperm DNA damage

Group

Parameter

Overall

≤30 y

31 – 40 y

<40 y

>40 y

  

(n = 472)

(n = 69)

(n = 298)

(n = 367)

(n = 105)

Varicocele (n = 253)

Volume (mL)

3.1 ± 1.5

3.4 ± 1.5

3.1 ± 1.5

3.2 ± 1.5

3.1 ± 1.9

Concentration (X106/mL)

42.01 ± 50.58

33.43 ± 39.19

31.25 ± 37.10

31.67 ± 37.42

35.91 ± 44.58

Motility (%)

44.7 ± 19.7

46.3 ± 14.5

41.9 ± 19.9

42.5 ± 19.1

40.0 ± 22.1

Normal Morphology (%)

3.2 ± 2.9

3.1 ± 2.6

2.8 ± 2.8

2.9 ± 2.7

2.9 ± 2.8

TAC (micromolar trolox)

1964.42 ± 683.77

1985.10 ± 674.43

1842.23 ± 699.77

1985.10 ± 674.43

1977.51 ± 737.31

ROS (RLU/sec/X106)

267.7 (59.3; 1277.3)

1078.7 (37.7; 8611.2)

484.7 (94; 2144.3)

316.6 (90.5; 1197.7)

265.6 ± 234.8 (41; 1322.7)

Sperm DNA damage (%)

19.9 ± 15.3

18.9 ± 11.0

17.6 ± 11.1

17.7 ± 11.7

22.0 ± 15.9

Smokers (n = 100)

Volume (mL)

3.1 ± 1.5

2.9 ± 1.4

3.0 ± 1.4

3.0 ± 1.4

2.6 ± 1.4

Concentration (X106/mL)

42.01 ± 50.58

30.86 ± 33.13

44.20 ± 50.23

42.14 ± 48.07

53.89 ± 77.41

Motility (%)

44.7 ± 19.7

45.2 ± 16.2

43.9 ± 17.5

44.2 ± 17.2

49.9 ± 25.5

Normal Morphology (%)

3.2 ± 2.9

3.8 ± 2.8

3.1 ± 3.0

3.2 ± 3.0

3.5 ± 2.6

TAC (micromolar trolox)

1964.42 ± 683.77

2146.67 ± 503.39

1842.23 ± 699.77

1883.75 ± 681.28

1683.08 ± 873.09

ROS (RLU/sec/X106)

267.7 (59.3; 1277.3)

1078.7 (37.7; 8611.2)

484.7 (94; 2144.3)

485 (90.6; 2238.3)

743.2 (215.8; 2744.2)

Sperm DNA damage (%)

19.9 ± 15.3

18.9 ± 11.0

17.6 ± 11.1

17.8 ± 11.0

16.0 ± 10.9

Alcohol users (n = 296)

Volume (mL)

3.1 ± 1.5

3.1 ± 1.5

3.1 ± 1.5

3.1 ± 1.3

3.1 ± 1.7

Concentration (X106/mL)

42.01 ± 50.58

33.43 ± 39.19

31.25 ± 37.10

43.67 ± 51.69

41.07 ± 55.82

Motility (%)

44.7 ± 19.7

46.3 ± 14.5

41.9 ± 19.9

44.7 ± 20.2

45.3 ± 25.5

Normal Morphology (%)

3.2 ± 2.9

3.1 ± 2.6

2.8 ± 2.8

3.2 ± 2.9

3.2 ± 3.1

TAC (micromolar trolox)

1964.42 ± 683.77

2250.50 ± 513.30

1898.15 ± 672.16a

1944.48 ± 660.19

1940.45 ± 733.36

ROS (RLU/sec/X106)

267.7 (59.3; 1277.3)

390.6 (150.5; 2434.8)

244.4 (59.3; 866.8)

265.6 (66.2; 964.6)

346.9 (58.2; 1494.3)

 

Sperm DNA damage (%)

19.9 ± 15.3

16.6 ± 12.3

19.8 ± 16.2

17.7 ± 11.7

24.1 ± 19.1

  1. The results are presented as mean ± SD for all the parameters except ROS which is presented as median (25th; 75th percentile).
  2. aP value <0.05 when 31-40 y group was compared with ≤30 y group.