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Table 1 Comparison of semen parameters between overall and 4 age groups

From: Infertile men older than 40 years are at higher risk of sperm DNA damage

Parameters

Overall

≤30 y

31 – 40 y

<40 y

>40 y

(n = 69)

(n = 298)

(n = 367)

(n = 105)

 

(n = 472)

69/472 (14.6%)

298/472 (63.1%)

367/472 (77.8%)

105/472 (22.2%)

Volume (mL)

3.1 ± 1.5

3.4 ± 1.5

3 ± 1.4

3.1 ± 1.4

3.1 ± 1.75

Concentration (X106/mL)

42.01 ± 50.58

36.66 ± 39.72

42.62 ± 52.23

41.50 ± 50.12

43.80 ± 52.37

Motility (%)

44.7 ± 19.7

44.3 ± 14.4

45.2 ± 19.5

45.0 ± 18.6

43.5 ± 22.9

Normal Morphology (%)

3.2 ± 2.9

3.1 ± 2.7

3.1 ± 2.9

3.1 ± 2.9

3.3 ± 3.1

TAC (micromolar trolox)

1964.42 ± 683.77

2114.02 ± 548.93

1948.80 ± 689.78

1974.03 ± 671.09

1930.87 ± 727.40

ROS (RLU/sec/X106)

267.7 (59.3; 1277.3)

311.1 (38.4; 1927.3)

256.9 (65.9; 1149.1)

265.6 (63.8; 1204.1)

429.9 (54.9; 1514.0)

Sperm DNA damage (%)

19.9 ± 15.3

16.7 ± 11.2

19.1 ± 14.6

18.7 ± 14. 1

24.4 ± 18.5a,b,c,d

  1. The results are presented as mean ± SD for all the parameters except ROS which is presented as median (25th; 75th percentile).
  2. aP value <0.05 when >40 y group was compared with the overall group.
  3. bP value <0.05 when >40 y group was compared with the group ≤30 y.
  4. cP value <0.05 when >40 y group was compared with the group 31-40 y
  5. dP value <0.05 when >40 y group was compared with the group <40 y.