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Table 2 Maximum concentrations of individual compounds tested in MVLN in vitro bioassays, induction relative to an E2 standard, and relative potency (REP) estimates

From: Estrogenic potency of bisphenol S, polyethersulfone and their metabolites generated by the rat liver S9 fractions on a MVLN cell using a luciferase reporter gene assay

Compounds Max. Conc. (μM) %-E2maxa Relative potency (REP)
REP50b REP20-80c
BPA 0.5 48.8 4.25 × 10−5 2.17 × 10−4 – 8.32 × 10−6
BPS 0.5 19.2 4.09 × 10−9 2.25 × 10−6 – 7.41 × 10−12
PES 0.5 - NAd  
  1. a%-E2max = Maximum response against the response at the highest concentration of E2 (E2max).
  2. bSingle point estimate of REP performed for the response of 50%-E2max.
  3. cREPs reported as the range of REP estimates generated from multiple points over a response range from 20- to 80%-E2max.
  4. dNA: not analyzed because the dose–response relationship was insufficient for estimation.