Morphology and quantity of MOFs in AQP8-deficient ovary. (A-F), representative images of MOFs in the HE-staining sections of AQP8 null ovaries. Scale bar, 40 μm. (G), a representative MOF in wild-type ovaries. (H), the numbers of MOF containing 2 or 3 oocytes in AQP8 null and wild-type ovaries. (I), the numbers of MOF per ovary at different ages of both genotypes. n = 5 ~ 8 (shown in Table 2). **: P < 0.01; ***: P < 0.001.