Skip to main content

Table 1 Clinical and hormonal features of women with PCOS and controls

From: Circulating levels and subcutaneous adipose tissue gene expression of pigment epithelium-derived factor in polycystic ovary syndrome and normal women: a case control study

Characteristic Control (n = 14) PCOS (n = 22) p p*
Age (years) 25.4 ± 2.4 23.9 ± 6.2 0.334 0.501
BMI (kg/m 2 ) 26.9 ± 5.5 30.8 ± 5.9 0.058  
Waist circumference (cm) 85.5 ± 9.8 90.9 ± 13.7 0.321 0.166
WHR 0.78 ± 0.06 0.83 ± 0.09 0.120 0.079
Ferriman-Gallwey score 1 (0–3) 9 (8–14) 0.003 0.003
Systolic BP (mmHg) 111 ± 4 117 ± 16 0.096 0.291
Diastolic BP (mmHg) 68 ± 6 75 ± 12 0.178 0.187
Glucose, fasting (mg/dL) 87 ± 6 88 ± 6 0.555 0.597
Glucose, 2 h (mg/dL) 89 ± 13 117 ± 25 0.007 0.006
Insulin, fasting (μIU/mL) 7.8 (4.3-11.2) 12 (8–19) 0.012 0.089
Insulin, 2 h (μIU/mL) 56.6 (36.8-94.7) 101 (46–175) 0.049 0.110
HOMA-IR 1.8 (1.3-2.8) 2.6 (1.8-4.2) 0.083 0.100
Triglycerides (mg/dL) 54 (40–72) 77 (48–119) 0.135 0.441
Total cholesterol (mg/dL) 144 ± 35 178 ± 40 0.013 0.026
HDL cholesterol (mg/dL) 48 ± 15 53 ± 9 0.272 0.277
LDL cholesterol (mg/dL) 83 ± 27 109 ± 35 0.024 0.036
LH (mIU/mL) 6.0 (4.0-7.6) 10.9 (6.5-18.6) 0.011 0.020
SHBG (nmol/L) 44.9 (35.3-59.3) 34.9 (18.4-47.8) 0.173 0.360
Total T (ng/mL) 0.60 (0.47-0.72) 1.26 (0.91-1.43) <0.001 0.001
FAI 4.7 (3.8-6.1) 9.4 (6.8-21.3) 0.001 0.101
  1. Values are expressed as mean ± SD or median (interquartile range). Statistical differences by unpaired two-tailed Student’s t-test or Mann–Whitney U test. BMI body mass index, BP blood pressure, FAI free androgen index, HDL high-density lipoprotein, HOMA-IR homeostasis model assessment, LDL low-density lipoprotein, LH luteinizing hormone, PCOS polycystic ovary syndrome, SHBG sex hormone-binding globulin, T testosterone, WHR waist to hip ratio. *Adjusted for BMI (linear regression).