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Table 4 Carnitine profile according to the number of embryos [μmol/L] [median (interquartile range)]

From: Acylcarnitine esters profiling of serum and follicular fluid in patients undergoing in vitro fertilization

  Serum embryo number Follicular fluid embryo number
  ≤ 6 N=28 >6 N=14 ≤ 6 N=28 >6 N=14
Analytes Median (IQR) Median (IQR) Median (IQR) Median (IQR)
free carnitine 28.623 (6.217) 24.955 (4.592)* 28.698 (4.914) 25.887 (5.559) #
Total acyl-carnitine 9.148 (2.2399 8.605 (1.500) 7.905 (1.713) 6.938 (1.972)
Total carnitine 37.100 (6.500) 32.739 (4.708)* 36.912 (5.838) 32.956 (6.978)
AC/FC ratio 0.317 (0.0749 0.333 (0.072) 0.279 (0.047) 0.281 (0.065)
Total short-chain acylcarnitines 7.893 (1.4489 7.598 (1.676) 7.316 (1.633) 6.482 (1.900)
Total medium-chain acylcarnitine 0.722 (0.2669 0.619 (0.242) 0.318 (0.121) 0.276 (0.073)
Total long-chain acylcarnitine 0.346 (0.051) 0.313 (0.093) 0.140 (0.024) 0.127 (0.042)
Short chain acylcarnitines  
  C2-carnitine 7.393 (1.445) 7.470 (1.123) 6.805 (1.525) 6.053 (1.844)
  C3-carnitine 0.183 (0.083) 0.183 (0.058) 0.218 (0.071) 0.178 (0.048)
  C4-carnitine 0.143 (0.063) 0.135 (0.052) 0.177 (0.085) 0.150 (0.032)
  C5-carnitine 0.060 (0.023) 0.048 (0.019) 0.053 (0.013) 0.048 (0.012)
  C5-OH carnitine 0.023 (0.010) 0.030 (0.010) 0.020 (0.007) 0.018 (0.003)
Medium chain acylcarnitines  
  C6-carnitine 0.028 (0.013) 0.025 (0.008) 0.020 (0.013) 0.020 (0.003)
  C8-carnitine 0.102 (0.036) 0.087 (0.046) 0.060 (0.023) 0.050 (0.025) #
  C8:1-carnitine 0.037 (0.018) 0.035 (0.025) 0.030 (0.018) 0.030 (0.026)
  C10-carnitine 0.220 (0.138) 0.206 (0.095) 0.073 (0.026) 0.055 (0.027) #
  C10:1-carnitine 0.163 (0.067) 0.140 (0.030) 0.073 (0.028) 0.070 (0.020)
  C12-carnitine 0.058 (0.022) 0.056 (0.020) 0.020 (0.004) 0.020 (0.006)
  C12:1-carnitine 0.068 (0.025) 0.058 (0.019) 0.022 (0.013) 0.020 (0.010)
Long chain acylcarnitines  
  C14-carnitine 0.023 (0.010) 0.022 (0.009) 0.010 (0.004) 0.010 (0.003)
  C14:1-carnitine 0.056 (0.023) 0.042 (0.030)* 0.020 (0.011) 0.017 (0.007)
  C16-carnitine 0.088 (0.026) 0.080 (0.0239 0.038 (0.008) 0.040 (0.012)
  C18-carnitine 0.033 (0.010) 0.028 (0.016) 0.013 (0.007) 0.013 (0.009)
  C18:1-carnitine 0.093 (0.029) 0.085 (0.040) 0.035 (0.011) 0.030 (0.013)
  C18:2-carnitine 0.055 (0.015) 0.047 (0.020) 0.020 (0.007) 0.020 (0.012)
Dicarboxylic acylcarnitines  
  C4DC-carnitine 0.028 (0.017) 0.030 (0.008) 0.023 (0.010) 0.027 (0.007) #
  C5DC-carnitine 0.092 (0.040) 0.078 (0.024) 0.055 (0.021) 0.050 (0.013)
  1. * p<0.05 compared to ≤ 6 embryo number in serum.
  2. # p<0.05 compared to ≤ 6 embryo number in follicular fluid.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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