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Table 3 Carnitine profile according to the number of oocytes [μmol/L] [median (interquartile range)]

From: Acylcarnitine esters profiling of serum and follicular fluid in patients undergoing in vitro fertilization

  Serum oocyte number Follicular fluid oocyte number
  ≤ 9 N=29 >9 N=13 ≤ 9 N=29 >9 N=13
Analytes Median (IQR) Median (IQR) Median (IQR) Median (IQR)
free carnitine 28.667 (6.090) 24.897 (4.137)* 28.768 (4.408) 25.515 (4.307) #
Total acyl-carnitine 9.147 (2.268) 8.767 (0.960) 7.997 (1.825) 6.810 (1.908) #
Total carnitine 36.940 (6.965) 32.869 (4.616)* 37.098 (5.845) 31.622 (6.026) #
AC/FC ratio 0.316 (0.075) 0.345 (0.073) 0.280 (0.0499 0.278 (0.053)
Total short-chain acylcarnitines 7.860 (1.492) 7.787 (1.172) 7.373 (1.8459 6.343 (1.802) #
Total medium-chain acylcarnitine 0.715 (0.257) 0.648 (0.275) 0.313 (0.1209 0.277 (0.065)
Total long-chain acylcarnitine 0.347 (0.060) 0.312 (0.072)* 0.140 (0.027) 0.127 (0.040)
Short chain acylcarnitines  
  C2-carnitine 7.393 (1.445) 7.470 (1.123) 6.833 (1.622) 5.880 (1.800) #
  C3-carnitine 0.185 (0.075) 0.180 (0.063) 0.210 (0.070) 0.177 (0.053) #
  C4-carnitine 0.143 (0.058) 0.140 (0.058) 0.170 (0.081) 0.153 (0.033)
  C5-carnitine 0.058 (0.025) 0.050 (0.020) 0.053 (0.013) 0.050 (0.010)
  C5-OH carnitine 0.023 (0.010) 0.030 (0.010) 0.020 (0.007) 0.020 (0.003)
Medium chain acylcarnitines  
  C6-carnitine 0.027 (0.013) 0.027 (0.007) 0.020 (0.013) 0.020 (0.003)
  C8-carnitine 0.100 (0.037) 0.093 (0.040) 0.060 (0.023) 0.053 (0.027)
  C8:1-carnitine 0.035 (0.018) 0.040 (0.028) 0.030 (0.018) 0.030 (0.027)
  C10-carnitine 0.215 (0.130) 0.215 (0.098) 0.070 (0.030) 0.055 (0.030) #
  C10:1-carnitine 0.160 (0.063) 0.140 (0.033) 0.073 (0.030) 0.070 (0.023)
  C12-carnitine 0.060 (0.023) 0.055 (0.018) 0.020 (0.007) 0.020 (0.003)
  C12:1-carnitine 0.070 (0.023) 0.057 (0.020) 0.020 (0.012) 0.020 (0.010)
Long chain acylcarnitines  
  C14-carnitine 0.023 (0.010) 0.020 (0.007) 0.010 (0.003) 0.010 (0.003)
  C14:1-carnitine 0.057 (0.023) 0.040 (0.030)* 0.020 (0.010) 0.017 (0.007)
  C16-carnitine 0.090 (0.027) 0.080 (0.037) 0.040 (0.007) 0.040 (0.013)
  C18-carnitine 0.033 (0.010) 0.027 (0.013) 0.013 (0.007) 0.013 (0.010)
  C18:1-carnitine 0.093 (0.032) 0.080 (0.037) 0.037 (0.010) 0.030 (0.010)
  C18:2-carnitine 0.057 (0.013) 0.043 (0.020) 0.020 (0.007) 0.020 (0.013)
Dicarboxylic acylcarnitines  
  C4DC-carnitine 0.030 (0.017) 0.030 (0.010) 0.023 (0.010) 0.027 (0.007) #
  C5DC-carnitine 0.090 (0.037) 0.075 (0.023) 0.053 (0.022) 0.050 (0.010)
  1. * p<0.05 compared to ≤ 9 oocyte number in serum.
  2. # p<0.05 compared to ≤ 9 oocyte number in follicular fluid.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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