Table 1 Dose–response effect of the GM-CSF on nuclear maturation of bovine oocytes matured in vitro

SOF

75

11/78 (14.6)

9/75 (12.0)

14/75 (18.7)

41/75 (54.7)

SOF + GM-CSF (1 ng/ml)

71

11/71 (15.5)

5/71 (7.0)

13/71 (18.3)

42/71 (59.2)

SOF + GM-CSF (10 ng/ml)

59

8/59 (13.6)

4/59 (6.8)

15/59 (25.4)

32/59 (54.2)

SOF + GM-CSF (100 ng/ml)

89

14/89 (15.7)

4/89 (4.5)

18/89 (20.2)

53/89 (59.6)

TCM

95

1/95 (1.0)

4/95 (4.2)

11/95 (11.6)

79/95 (83.2*)