Table 3 COH outcome
Non OCP group | OCP group | p-value | ||
|---|---|---|---|---|
Clinical outcome | Cycles (n) | 57 | 45 | |
% cancellation before retrieval | 15.8% (n = 9) | 13.3% (n = 6) | NS | |
% oocytes retrieval (n) | 84.2% (n = 48) | 86.7% (n = 39) | NS | |
r-FSH starting dose (IU) | 125 [100–200] | 125 [100–150] | NS | |
Duration of stimulation (days) | 11 [8.45-15.55] | 11 [9.0-14.0] | NS | |
Total dose of r-FSH (IU) | 1437.5 [872.5-2555] | 1462.5 [1000–2250] | NS | |
% OHSS | 16.6% (n = 8) | 10.2% (n = 4) | NS | |
Days of GnRH agonist (n) | 25 [20–33] | 24 [21–29] | P = 0.011 | |
Endometrium thickness | D1 (mm) | 2.0 [2.0-5.8] | 3.0 [2.0-6.3] | P = 0.001 |
HCG-D (mm) | 11.0 [8.5-14.8] | 10.0 [7.9-13.0] | P = 0.002 | |
Delta (mm) (HCG-D – D1) | 8.0 [4.4-12] | 6.5 [2.3-10.3] | P < 0.0001 | |
Oocytes | Total oocytes (n) | 14 [7.5-24.0] | 14 [7.0-27.0] | NS |
Lysed oocytes (n) | 1 [0–5.6] | 2 [0–6.0] | NS | |
Meta II oocytes (n) | 11 [4.0-19.0] | 8 [5.0-22.0] | NS | |
Ratio meta II oocytes/≥ 15 mm follicles | 1.44 (+/−0.92) | 1.32 (+/−0.80) | NS | |
Embryos | Embryos (n) | 6 [0.5-14.5] | 5 [0.0-13.0] | NS |
Fertilization rate | 63% (+/−21) | 56% (+/−26) | NS | |
“Top quality” embryos (n) | 2 [0.0-7.0] | 1 [0.0-8.0] | NS | |
Cycles with embryo transfer (n) | 46 | 33 | ||
One embryo transferred (%) | 6.5 (n = 3) | 18.2 (n = 6) | NS | |
Two embryos transferred (%) | 87 (n = 42) | 81.8 (n = 27) | NS | |
Three embryos transferred (%) | 2.2 (n = 1) | 0 (n = 0) | NS | |
Cycles with freezing (%) | 58.3 (n = 28) | 51.2 (n = 20) | NS | |
Frozen embryos (n) | 4 [1.0-11.0] | 3.5 [1.0-10.0] | NS | |
Recovery rate after thawing | 72,8% | 77,9% | NS | |
Frozen-thawed embryo transfers (n) | 19 | 21 | ||
Clinical pregnancy rate per frozen-thawed embryo transfer | 31,6% (n = 6) | 38% (n = 8) | NS | |
Ongoing pregnancy rate per frozen-thawed embryo transfer | 31,6% (n = 6) | 38% (n = 8) | NS | |