Table 3 Ovarian response and clinical outcomes: received hCG as soon as criterion was reached or 1-day delay (Analysis Set 1)
| Â | Corifollitropin alfa | rFSH | ||
|---|---|---|---|---|
| Â | No delay | Delay | No delay | Delay |
|  | n = 492 | n = 188 | n = 516 | n = 191 |
Duration of stimulation, days, mean (SD) | 9.4 (1.4) | 9.9 (1.3) | 9.1 (1.3) | 9.5 (1.0) |
Follicles on day 8 ≥11 mm, mean (SD) | 12.8 (6.6) | 12.8 (5.5) | 11.4 (5.9) | 11.5 (5.1) |
Serum E 2 on day 8, pmol/l, median (P5, P95) | 3019 | 2753 | 2965 | 3097 |
(837, 8588) | (1013, 7634) | (1017, 8184) | (1046, 7450) | |
Follicles on day of hCG ≥11 mm, mean (SD) | 16.0 (6.9) | 15.6 (5.5) | 13.8 (6.2) | 13.6 (5.0) |
E 2 on day of hCG, pmol/l, median (P5, P95) | 4551 | 4881 | 4477 | 4331 |
(1629, 11,450) | (1883, 11,964) | (1718, 9872) | (1758, 10,349) | |
No. of oocytes retrieved, mean (SD) | 14.2 (8.3) | 14.1 (6.7) | 12.4 (6.6) | 13.3 (6.3) |
No. of embryos obtained on day 3, mean (SD) | 8.1 (5.7) | 8.9 (4.9) | 7.4 (4.7) | 7.8 (4.5) |
No. of GQEs obtained on day 3, mean (SD) | 4.4 (4.3) | 5.4 (4.2) | 4.3 (3.7) | 4.8 (3.9) |
No. of GQEs transferred, mean (SD) | 1.2 (0.8) | 1.4 (0.7) | 1.3 (0.8) | 1.3 (0.8) |
Cycle cancellation rate, n (%) | 45 (9.1) | 10 (5.3) | 23 (4.5) | 10 (5.2) |