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Table 3 Ovarian response to stimulation and outcome of IVF treatment according to LH genotype

From: A common polymorphic allele of the LH beta-subunit gene is associated with higher exogenous FSH consumption during controlled ovarian stimulation for assisted reproductive technology

  Group Awild-type LH n = 196 Group Bv-betaLH n = 24 p value A vs B
Estradiol Day S1 (nmol/L) 0.1 ± 0.1 0.1 ± 0.1 NS
Estradiol Day S8 (nmol/L) 3.9 ± 2.8 3.4 ± 3.0 NS
Androstenedione on Day of trigger (ng/mL) 1.5 ± 0.8 2.1 ± 1.3 0.012
Androstenedione on OPU (ng/mL) 5.35 ± 2.4 5.53 ± 2.3 NS
LH (IU/L) Day S1 1.9 ± 0.9 2.1 ± 1.3 NS
LH (IU/L) Day S8 1.9 ± 1.25 1.8 ± 0.95 NS
LH (IU/L) Day OPU 0.1 ± 0.1 0.1 ± 0.7 NS
Cumulative FSH dose (IU) 1959.8 ± 736.45 2435.9 ± 932.8 0.048
N. mature oocytes retrieved* 8.6 ± 4.9 7.3 ± 4.85 NS
N. embryos transferred* 1.6 ± 0.8 1.3 ± 0.6 0.042
Fertilization rate (%) 52 46 NS
Positive betahCG (%) 37 45 NS
  1. Values are expressed as mean ± SD.
  2. Abbreviations: NS not statistically significant; oPu ovum pick up.