Skip to main content

Table 3 Ovarian response to stimulation and outcome of IVF treatment according to LH genotype

From: A common polymorphic allele of the LH beta-subunit gene is associated with higher exogenous FSH consumption during controlled ovarian stimulation for assisted reproductive technology

 

Group Awild-type LH n = 196

Group Bv-betaLH n = 24

p value A vs B

Estradiol Day S1 (nmol/L)

0.1 ± 0.1

0.1 ± 0.1

NS

Estradiol Day S8 (nmol/L)

3.9 ± 2.8

3.4 ± 3.0

NS

Androstenedione on Day of trigger (ng/mL)

1.5 ± 0.8

2.1 ± 1.3

0.012

Androstenedione on OPU (ng/mL)

5.35 ± 2.4

5.53 ± 2.3

NS

LH (IU/L) Day S1

1.9 ± 0.9

2.1 ± 1.3

NS

LH (IU/L) Day S8

1.9 ± 1.25

1.8 ± 0.95

NS

LH (IU/L) Day OPU

0.1 ± 0.1

0.1 ± 0.7

NS

Cumulative FSH dose (IU)

1959.8 ± 736.45

2435.9 ± 932.8

0.048

N. mature oocytes retrieved*

8.6 ± 4.9

7.3 ± 4.85

NS

N. embryos transferred*

1.6 ± 0.8

1.3 ± 0.6

0.042

Fertilization rate (%)

52

46

NS

Positive betahCG (%)

37

45

NS

  1. Values are expressed as mean ± SD.
  2. Abbreviations: NS not statistically significant; oPu ovum pick up.