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Table 2 Quality of controlled studies passing eligibility criteria presented by stratification of research methodology and Newcastle-Ottawa scale a (for non-randomised observational studies)

From: Efficacy of dehydroepiandrosterone to improve ovarian response in women with diminished ovarian reserve: a meta-analysis

Author/Year

Design

Randomisation

Blinding

Sample size estimation

Analysis

Newcastle-Ottawa scale

Selection

Comparability

Outcome

Barad D, et al. (2007)

Case -control study

None

None

N/A

Intention to treat analysis

***

*

**

Wiser A, et al. (2010)

Randomised controlled study

-Computer generated random numbers

None

Not done

Intention to treat analysis

   
  

- allocation concealment by sealed envelope

  

(No-drop out)

   

Gleicher N, et al. (2010)

Case -control study

None

None

N/A

Intention to treat analysis

***

*

***

  1. a Wells GA et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality if nonrandomized studies in meta-analysis, available from: URL: http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp [cited 2012 June 1].