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Table 2 Quality of controlled studies passing eligibility criteria presented by stratification of research methodology and Newcastle-Ottawa scale a (for non-randomised observational studies)

From: Efficacy of dehydroepiandrosterone to improve ovarian response in women with diminished ovarian reserve: a meta-analysis

Author/Year Design Randomisation Blinding Sample size estimation Analysis Newcastle-Ottawa scale
Selection Comparability Outcome
Barad D, et al. (2007) Case -control study None None N/A Intention to treat analysis *** * **
Wiser A, et al. (2010) Randomised controlled study -Computer generated random numbers None Not done Intention to treat analysis    
   - allocation concealment by sealed envelope    (No-drop out)    
Gleicher N, et al. (2010) Case -control study None None N/A Intention to treat analysis *** * ***
  1. a Wells GA et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality if nonrandomized studies in meta-analysis, available from: URL: http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp [cited 2012 June 1].