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Figure 4 | Reproductive Biology and Endocrinology

Figure 4

From: Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4)

Figure 4

Inhibition of Notch signaling with a γ-secretase inhibitor (Compound E) blocked follicle development to the preovulatory stage. Immunohistochemistry for PECAM (brown) counterstained with hematoxylin. Please note disorganized appearance of PECAM staining in treatment group. A) three control preovulatory follicles (10× magnification) B) γ-secretase inhibitor treated follicles (10× magnification) C) Enlargement of treatment follicle in B (20 × magnification).

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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