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Table 2 Detailed list of classification of 35 proteins based on their presence, abundance, and differential expression

From: Functional proteomic analysis of seminal plasma proteins in men with various semen parameters

No. Protein Names NCBI Accession No. UniProt Accession No. No. of samples Proteins present in groups Low abundant proteins (SC ≤ 10) Differentially Expressed Proteins (in NA, OA, and ON) compared to NN Significant proteins in groups
1 prolactin-induced protein 4505821 P12273 12 NN(5), NA(4), OA(2), ON(1)    NN, NA, OA, ON
2 semenogelin II precursor 4506885 Q02383 12 NN(5), NA(4), OA(2), ON(1)    NN, NA, OA, ON
3 albumin preproprotein 4502027 P02768 12 NN(5), NA(4), OA(2), ON(1)    NN, NA, OA, ON
4 lactotransferrin 54607120 P02788 12 NN(5), NA(4), OA(2), ON(1)    NN, NA, OA, ON
5 epididymal secretory protein E1 precursor 5453678 P61916 12 NN(5), NA(4), OA(2), ON(1)    NN, NA, OA, ON
6 extracellular matrix protein 1 isoform 1 precursor 221316614 Q16610 12 NN(5), NA(4), OA(2), ON(1)    NN, NA, OA, ON
7 prosaposin isoform a preproprotein 11386147 P07602 12 NN(5), NA(4), OA(2), ON(1)    NN, NA, OA, ON
8 cathepsin D preproprotein 4503143 P07339 12 NN(5), NA(4), OA(2), ON(1)    NN, NA, OA, ON
9 prostate specific antigen isoform 1 preproprotein 4502173 Q546G3 12 NN(5), NA(4), OA(2), ON(1)   ↑ in OA NN, NA, OA, ON
10 zinc alpha-2-glycoprotein 1 4502337 P25311 12 NN(5), NA(4), OA(2), ON(1)   ↑ in ON NN, NA, OA, ON
11 clusterin isoform 1 42716297 P10909 12 NN(5), NA(4), OA(2), ON(1) Low in ON ↓ in ON NN, NA, OA
12 mucin 6, gastric 151301154 Q6W4X9 11 NN(4), NA(4), OA(2), ON(1)   ↓ in NA NN, NA, OA, ON
13 cystatin S precursor 4503109 P01036 11 NN(4), NA(4), OA(2), ON(1) Low in ON ↓ in NA, OA, ON NN, NA, OA
14 galectin 3 binding protein 5031863 Q08380 11 NN(5), NA(3), OA(2), ON(1) Low in OA and ON ↓ in OA, ON NN, NA
15 semenogelin I isoform b preproprotein 38049014 P04279 10 NN(3), NA(4), OA(2), ON(1)   ↑ in OA NN, NA, OA, ON
16 prostatic acid phosphatase precursor 6382064 P15309 10 NN(4), NA(3), OA(2), ON(1) Low in ON ↓in NA, ON NN, NA, OA
17 cystatin C precursor 4503107 P01034 9 NN(4), NA(3), OA(1), ON(1)   ↓in OA NN, NA, OA, ON
18 tissue inhibitor of metalloproteinase 1 precursor 4507509 Q6FGX5 8 NN(3), NA(3), OA(1), ON(1)   ↑ in ON NN, NA, OA, ON
19 beta 2 microglobulin precursor 4757826 P61769 8 NN(3), NA(3), OA(1), ON(1) Low in OA ↓ in OA; Up in ON NN, NA, ON
20 DJ-1 protein 31543380 Q99497 6 NN(2), NA(3), ON(1)   ↑ in NA, ON NN, NA, ON
21 ankyrin repeat domain 11 56676397 Q6UB99 4 NA(1), OA(2), ON(1) Low in NA and ON ↓ in OA, ON OA
22 orosomucoid 1 precursor 167857790 P02763 2 NN(2), NA(1) Low in NA ↓in NA NN
23 serine proteinase inhibitor, clade A, member 1 50363217 P01009 8 NN(3), NA(3), OA(1), ON(1)   ↑ in NA,ON; ↓ in OA NA, OA, ON
24 transferrin 4557871 Q06AH7 6 NN(2), NA(3), OA(1) Low abundant ↑ in NA, OA NONE
25 secretory leukocyte peptidase inhibitor precursor 4507065 P03973 5 NN(1), NA(3), OA(1) Low abundant ↑ in NA, OA NONE
26 ubiquitin and ribosomal protein S27a precursor 4506713 P62979 4 NN(2), NA(1), OA(1) Low abundant ↓ in NA, OA NONE
27 protein tyrosine phosphatase, receptor type, sigma isoform 1 precursor 104487006 Q13332 4 NN(1), NA(2), ON(1) Low abundant ↑ in NA, ON NONE
28 acidic epididymal glycoprotein-like 1 isoform 1 precursor 25121982 P54107 3 NN(2), NA(1) Low abundant ↓in NA NONE
29 prostaglandin H2 D-isomerase 32171249 P41222 5 NN(2), NA(2), OA(1) Low abundant   NONE
30 cathepsin B preproprotein 4503139 P07858 6 NN(3), NA(3) Low abundant   NONE
31 expressed in prostate and testis 19923082 Q8WXA2 4 NN(2), NA(1), OA(1) Low abundant   NONE
32 orosomucoid 2 4505529 P19652 1 NN(1) Low abundant   NONE
33 CD177 molecule 110735433 Q8N6Q3 3 NA(1), OA(1), ON(1n with (1)) Low abundant   NONE
34 carboxypeptidase E preproprotein 4503009 P16870 9 NN(3), NA(3), OA(2), ON(1) Low in OA and ON   NN, NA
35 fibronectin 1 isoform 2 preproprotein 47132551 P02751 10 NN(4), NA(4), OA(1), ON(1) Low in ON   NN, NA, OA
  1. NN = normal sperm count and normal morphology; NA = normal sperm count and abnormal morphology; ON = oligozoospermia and normal morphology; OA = oligozoospermia and abnormal morphology; number in the parenthesis indicates the number of samples.