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Figure 3 | Reproductive Biology and Endocrinology

Figure 3

From: Maternal nutrient restriction in the ewe from early to midgestation programs reduced steroidogenic enzyme expression and tended to reduce progesterone content of corpora lutea, as well as circulating progesterone in nonpregnant aged female offspring

Figure 3

Enzyme activities from livers of aged ewe offspring of control and nutrient restricted dams for hepatic enzymes involved in progesterone metabolism: cytochrome P450 2C (CYP2C), cytochrome P450 3A (CYP3A), aldo- keto reductase 1C (AKR1C) and cytochrome P450 reductase (P450) . Control (n=4, open bars) and nutrient restricted (n=4, solid bars) offspring. No treatment differences were detected. The dashed line separates activities to be read on the left versus right y-axes. There were no significant effects of treatment on the activity of any enzyme.

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