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Figure 4 | Reproductive Biology and Endocrinology

Figure 4

From: Inhibition of ovine in vitro fertilization by anti-Prt antibody: hypothetical model for Prt/ZP interaction

Figure 4

Prt/ZP domain, predicted binding. (A) Prt/ZP2 (ZP domain) model; (B) Prt/ZP3(ZP domain) model; (C) Prt/ZP4(ZP domain) model. ZP domains and Prt are shown respectively in surface and cartoon representations. N-terminal region of ZP domain is coloured in yellow-orange. C-terminal region of ZP domain is coloured in pale cyan. Expected Internal Hydrophobic Patch (IHP) interdomain linker (using the mouse and human IHP linkers as templates; as described in Jovine et al. [67]), are coloured in magenta. Polar contacts with corresponding ZP amino acids are indicated with one-letter code. Based on UniProtKB/Swiss-Prot sequences [Prt (A4ULE2); ZP2 (Q9BH10; a.a. 366–632); ZP3(P48830; a.a. 44–306); ZP4(Q9BH11; a.a. 188–465)].

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