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Figure 7 | Reproductive Biology and Endocrinology

Figure 7

From: Protective effects of nuclear factor erythroid 2-related factor 2 on whole body heat stress-induced oxidative damage in the mouse testis

Figure 7

Proposed model of Nrf2-mediated protection to whole body heat stress in mice testes. ROS production induced by heat stress was inhibited by the antioxidative system in cytoplasm. Increased ROS stimulated Nrf2-antioxidant system and up-regulated CuZn-SOD concentration in spermatogonia. Thereby, the antioxidative system was enhanced and efficiently protected testes against oxidative damage.

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