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Table 2 Follicle count of bilateral ovaries in the 6 groups

From: Combination of a GnRH agonist with an antagonist prevents flare-up effects and protects primordial ovarian follicles in the rat ovary from cisplatin-induced toxicity: a controlled experimental animal study

Groups

n

Primordial follicle

Growing follicle

Mature follicle

Total

Control

12

370.5±6.9

235.3±31.1

54.6±17.1

660±24.4

CDDP

12

136.5±23.1a

28.6±4.7a

9.1±6.3a

174.2±32.5a

GnRHa

12

213.2±22.3abc

41.6±12.3a

13±10.6a

267.8±34.2abc

GnRHant

12

227.5±8.9abc

71.5±12.0ab

19.5±6.8ab

318.5±6.9abc

  1. aP<0.01 vs. control group; bP<0.01 vs. CDDP group; cP<0.01 vs. combination (lng) group; dP<0.05 vs. CDDP group.
  2. Data are expressed as the mean ± standard error.