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Table 3 Controlled ovarian stimulation and IVF outcome by number of transferred embryos

From: IVF outcome is optimized when embryos are replaced between 5 and 15 mm from the fundal endometrial surface: a prospective analysis on 1184 IVF cycles

  All EFD (mm) p
   <5 5-9.9 10-15 >15  
  (n = 1184) (n = 59) (n = 548) (n = 429) (n = 148)  
n. of pregnancies All 476 24 227 186 39  
SET 49 3 21 21 4  
DET 427 21 206 165 35  
CPR/ET (%) All 40.2 40.7 41.4 43.4 26.4* 0.003
SET 17.2 20.0 18.3 18.7 9.5 ns
DET 44.3 42.9 45.3 48.1 30.2* 0.02
Implantation rate (IR) All 19.9 19.7 20.9 20.9 12.9* 0.02
SET 18.2 22.2 19.6 19.5 9.7 ns
DET 20.4 15.6 21.8 21.5 13.8* 0.04
Abortion rate (AR) All 21.4 42.1 17.6 22.0 26.5 ns
SET 22.4 0 19.0 33.3 0 ns
DET 21.3 47.6 17.5 20.6 28.6 ns
Ongoing pregnancies at 10 W All 374 14 187 145 29  
SET 38 3 17 14 4  
DET 336 11 170 131 25  
Ongoing PR/ET All 31.6 23.7 34.1 33.8 19.6 ns
SET 13.4 20.0 14.8 12.5 9.5 ns
DET 37.3 25.0 39.3 41.3 23.6 ns
  1. Patients were subgrouped according to the site at which embryos were transferred (EFD = distance between the hyperecogenic spot and the basal layer of the endometrial fundus) and according to the number of transferred embryos (SET = single embryo transfer; n = 284; DET = double embryo transfer; n = 900).
  2. *significance level of this subgroup vs. 5–9.9 and 10–15.