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Table 3 Time and dose-dependent effects of norepinephrine on progesterone production

From: Norepinephrine stimulates progesterone production in highly estrogenic bovine granulosa cells cultured under serum-free, chemically defined conditions

Time (h) Norepinephrine (M)
0 10-9 10-8 10-7
0 46.9 ± 38.5a 46.9 ± 38.5a 46.9 ± 38.5a 46.9 ± 38.5a
48 37.0 ± 6.0ab,A 125.5 ± 43.0ab,AB 171.0 ± 40.5b,BC 251.0 ± 38.5b,C
96 139.9 ± 49.7b 175.0 ± 43.0b 188.3 ± 43.0b 154.8 ± 43.0ab
  1. Time and dose-dependent effects of norepinephrine on progesterone (ng/ml) production by highly estrogenic bovine granulosa cells cultivated with 0.1% PVA supplementation.
  2. a, b Means within a column with unlike superscripts differ (P < 0.05); A, B,C Means within a row with unlike superscripts differ (P < 0.05); values are least square means ± SEM (n=5 independent cultures).