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Table 2 Time and dose-dependent effects of norepinephrine on estradiol production

From: Norepinephrine stimulates progesterone production in highly estrogenic bovine granulosa cells cultured under serum-free, chemically defined conditions

Time (h) Norepinephrine (M)
0 10-9 10-8 10-7
0 0.11 ± 0.4a 0.11 ± 0.4a 0.11 ± 0.4a 0.11 ± 0.4a
48 1.83 ± 0.4b 2.61 ± 0.42b 2.39 ± 0.4b 2.1 ± 0.38b
96 2.25 ± 0.5b 2.25 ± 0.42b 2.37 ± 0.4b 2.60 ± 0.4b
  1. Time and dose-dependent effects of norepinephrine on estradiol (ng/ml) production by highly estrogenic bovine granulosa cells cultivated with 0.1% PVA supplementation.
  2. a, b Means within a column with unlike superscripts differ (P < 0.05); values are least square means ± SEM (n=5 independent cultures).