The proto-oncogene c-src is involved in primordial follicle activation through the PI3K, PKC and MAPK signaling pathways

Table 1 C-src involved in p-PI3K, p-PKC and p-ERK1/2 signal cascades in primordial follicle development

Treatment	The relationship and the changes
Treatment	*c-src*→	p-PI3K→	p-PKC→	p-EPK1/2→	follicle growth
c-src siRNA	↓	↓	↓	↓	↓
LY294002	-	↓	↓	↓	↓
Calphostin	-	-	↓	↓	↓
PD98059	-	-	-	↓	↓

ISSN: 1477-7827