Figure 3From: PreImplantation Factor (PIF) promoting role in embryo implantation: increases endometrial Integrin-α2β3, amphiregulin and epiregulin while reducing betacellulin expression via MAPK in deciduasPIF down-regulates activated p-MAPK involved in HESC proliferative pathway. HESC were cultured in presence of 100nM sPIF for 24 hours at the end of culture lysates phospho-proteins were analyzed by using BioPlex kit in triplicate determining (Mean+/−SEM), P < 0.05. a)p-MEK-1 b) p-ERK1,2, c) p-p38MAPK. The decrease in all three kinases was marked as compared to PBS control.Back to article page