Table 1 Comparison between the ICSI and IMSI procedures

Cycles

50

50

25

25

25

25

Leukocytes in semen (x10⁶)(mean ± SD)

1.5 ± 1.8 (0–8)

2.5 ± 7.5 (0–50)

0.41

2.4 ± 1.7 (1–8)

4.8 ± 10.5(1–50)

0.10

0.4 ± 0.3 (0–0.8)

0.4 ± 0.3 (0–0.8)

0.76

Female age (years)

34.4 ± 3.6

34.8 ± 3.9

0.67

34.4 ± 3.8

34.8 ± 4.1

0.75

34.5 ± 3.6

34.8 ± 3.8

0.79

Male age (years)

36.9 ± 5.0

37.2 ± 5.6

0.80

37.2 ± 5.0

37.4 ± 5.2

0.91

36.7 ± 5.0

37.0 ± 6.0

0.81

Aetiology (%)

0.10

0.43

0.26

Male

48% (24/50)

40% (20/50)

56% (14/25)

36% (9/25)

40% (10/25)

44% (11/25)

Idiopathic

16% (8/50)

24% (12/50)

16% (4/25)

20% (5/25)

16% (4/25)

28% (7/25)

Tuboperitoneal

10% (5/50)

16% (8/50)

12% (3/25)

24% (6/25)

8% (2/25)

8% (2/25)

Endometriosis

18% (9/50)

8% (4/50)

8% (2/25)

4% (1/25)

28% (7/25)

12% (3/25)

Tuboperitoneal + endometriosis

6% (3/50)

----

4% (1/25)

----

8% (2/25)

---

Male + tuboperitoneal

2% (1/50)

8% (4/50)

4% (1/25)

8% (2/25)

----

8% (2/25)

Male + t endometriosis

----

4% (2/50)

----

8% (2/25)

---

Semen parameters^a (mean ± SD)

Total sperm count (x10⁶/mL)

56.5 ± 49.5

50.9 ± 40.3

0.87

43.2 ± 44.5

41.0 ± 34.8

0.70

69.7 ± 51.5

60.8 ± 43.6

0.58

Motility (% spermatozoa)

-rapid + slow\progression

43.1 ± 19.7

51.4 ± 22.2

0.09

35.8 ± 17.8

44.3 ± 21.8

0.17

50.7 ±17.9

58.6 ± 20.8

0.22

-non-progressive

11.5 ± 11.4

9.6 ± 11.2

0.08

11.9 ± 12.3

10.5 ± 13.7

0.17

11.2 ± 10.3

8.6 ± 8.3

0.25

-immotile

42.6 ± 20.6

38.6 ± 20.4

0.42

50.4 ± 23.6

45.8 ± 21.0

0.50

35.9 ± 13.6

31.4 ± 17.3

0.36

Morphology

-normal forms (%)

14 ± 10.5

----

10.1 ± 0.8

----

17.9 ± 20.3

----

Vitality (%)

46.9 ± 19.2

44.2 ± 19.6

0.66

45.1 ± 17.5

43.1 ± 20.5

0.81

48.8 ± 20.9

45.3 ± 18.7

0.52

MSOME ^b (%)

-normal spermatozoa

----

1.13 ± 1.65

----

0.92 ± 1.43

----

1.35 ± 1.87

-spermatozoa with vacuoles occupying >50% of the nuclear area

----

35.9 ± 23.05

----

37.8 ± 20.2

34.0 ± 25.9

Metaphase II oocytes (n)

7.8 ± 4.3

7.8 ± 5.2

0.69

8.5 ± 4.2

8.2 ± 5.7

0.66

7.3 ± 4.2

7.4 ± 4.9

0.81

Fertilisation rate (%)

59.9 ± 28.7

63.5 ± 26.5

0.55

57.9 ± 30.2

67.6 ± 24.6

0.35

61.9 ± 27.7

59.5 ± 28.1

0.86

Embryos transfer (n)

2.1 ± 0.9

2.4 ± 0.8

0.21

2.2 ± 0.9

2.3 ± 0.8

0.90

2.1 ± 1.0

2.6 ± 0.9

0.10

Implantation rate (%)

13.2% (14/106)

17.2% (19/111)

0.54

12.3% (7/54)

17.5% (10/57)

0.68

13.5% (7/52)

16.7% (9/54)

0.84

Pregnancy/cycle (%)

24% (12/50)

26% (13/50)

0.81

24% (6/25)

28% (7/25)

0.74

24% (6/25)

24% (6/25)

1

Miscarriage (%)

0

7.7% (1/13)

0.32

0

14.3% (1/7)

0.33

0

0

----

Ongoing pregnancy/cycle (%)

24% (12/50)

24% (12/50)

1

24% (6/25)

24% (6/25)

1

24% (6/25)

24% (6/25)

1

Live birth/cycle (%)

24% (12/50)

24% (12/50)

1

24% (6/25)

24% (6/25)

1

24% (6/25)

24% (6/25)

1