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Table 2 Obstetrical outcome in pregnancies with donated oocytes versus individually matched pregnancies with autologous oocytes

From: Obstetric outcome in donor oocyte pregnancies: a matched-pair analysis

 

All pregnancies

Singletons

Twins

 

DO

AO

P

DO

AO

P

DO

AO

P

n = 205 (%)

n = 205 (%)

n = 148 (%)

n = 148 (%)

n = 57 (%)

n = 57 (%)

Vaginal bleeding

         

 1st trimester

42/204

21/204

0.005

32/148

20/148

0.08

10/57

1/57

0.01

(20.6)

(10.3)

(21.8)

(13.6)

(17.5)

(1.8)

 2nd trimester

5/205

6/204

1

3/148

5/147

0.73

2/57

1/57

1

(2.4)

(2.9)

(2)

(3.4)

(3.5)

(1.8)

 3rd trimester

3/205

3/205

1

2/148

3/148

1

1/57

0/57

1

(1.5)

(1.5)

(1.4)

(2)

(1.8)

(0)

Nausea and vomiting

         

 1st trim. Nausea

44/205

48/205

0.70

30/148

32/148

0.88

14/57

16/57

0.82

(21.5)

(23.4)

(20.3)

(21.6)

(24.6)

(28.1)

 Hospital admission because of hyperemesis

5/204

0/204

0.06

2/147

0/147

0.50

3/57

0/57

0.25

(2.5)

(0)

(1.4)

(0)

(5.3)

(0)

Hypertensive disorders

         

 Pregnancy induced hypertension

39/204

17/204

0.002

25/147

13/147

0.05

14/57

4/57

0.02

(19.1)

(8.3)

(17.0)

(8.8)

(24.6)

(7.0)

 Pre-eclampsia

24/204

13/204

0.07

15/147

8/147

0.21

9/57

5/57

0.29

(11.8)

(6.4)

(10.2)

(5.4)

(15.8)

(8.8)

 HELLP syndrome

2/204

1/204

1

1/147

1/147

1

1/57

0/57

1

(1.0)

(0.5)

(0.7)

(0.7)

(1.8)

(0)

Abnormal Placentation

         

 Placenta praevia

4/204

6/204

0.69

4/147

6/147

0.69

0/57

0/57

1

(2.0)

(2.9)

(2.7)

(4.1)

(0)

(0)

 Placental abruption

0/204

2/204

0.5

0/147

2/147

0.50

0/57

0/57

1

(0)

(1.0)

(0)

(1.4)

(0)

(0)

Preterm labour

         

 pPROM

7/204

10/204

0.61

2/147

5/147

0.38

5/56

5/56

1

(3.4)

(4.9)

(1.4)

(3.4)

(8.9)

(8.9)

 Preterm labour

32/204

44/204

0.12

15/147

26/147

0.10

17/57

18/57

1

(15.7)

(21.6)

(10.2)

(16.7)

(29.8)

(31.6)

Gestational diabetes

15/204

7/204

0.10

11/147

4/147

0.07

4/57

3/57

1

(7.4)

(3.4)

(7.5)

(2.7)

(7.0)

(5.3)

Cholestasis

1/205

2/205

1

0/147

1/147

1

1/57

1/57

1

(0.5)

(01.0)

(0)

(0.7)

(1.8)

(1.8)

  1. Paired t tests for continuous variables and McNemar test for categorical variables.
  2. DO Donated oocyte; AO Autologous oocyte.
  3. Categorical variables are presented as numerator and denominator values (%), and continuous variables as mean (SD, standard deviation) for each group of interest.