Table 1 Demographic and clinical data on the 35 participants with PWS: Group A: primary hypogonadism; Group B: central hypogonadism; Group C: partial gonadal & central dysfunction; Group D: mild central and severe gonadal dysfunction
From: The FSH-inhibin axis in prader-willi syndrome: heterogeneity of gonadal dysfunction
Group A (n=10) | Group B 2 (n=8) | Group C (n=9) | Group D 3 (n=8) | |
|---|---|---|---|---|
Males/Females4 | 9 / 1 | 4/ 4 | 4 / 5 | 2 / 6 |
Genetic subtype DEL/UPD/IC | 8 / 2 | 5 / 2 / 1 | 4 / 5 | 4 / 4 |
Age (y) (mean±SD) | ||||
Males | 23.7±6.3 | 21.2±5.5 | 21.5±4.9 | 19.5±2.1 |
Females | 17.4 | 24.0±2.7 | 24.2±4.9 | 23.2±5.7 |
Height (cm) | ||||
Males | 154.0±8.2 | 152.0±5.3 | 155.6±9.5 | 151.5±4.2 |
Females | 154 | 142.5±11.6 | 148.3±4.1 | 141.1±13.0 |
BMI (cm/kg2) | ||||
Males | 26.2±3.8 | 36.6±4.7 | 35.3±17.2 | 28.4±8.1 |
Females | 28.7 | 35.5±1.6 | 37.2±15.2 | 36.7±13.3 |
Pubic hair1 | ||||
Males | 4.2±0.8 | 2.3±1.5 | 3.8±1.3 | 4.5±0.7 |
Females | 3 | 4.0±0.0 | 4.6±0.5 | 3.0±1.7 |
Breast development 1 | 3 | 4.0±0.0 | 4.4±0.6 | 3.4±0.5 |
Penis length (cm) | 8.2±1.7 | 5.3±0.3 | 8.5±3.7 | 7.3±1.8 |
Testes volume 1 | 1.7±0.9 | 1.5±1.0 | 2.6±1.3 | 1.5±0.7 |