Figure 1

Serum levels of LH, FSH, AMH and inhibin B (INB) in the four groups of PWS males and females, serum estradiol levels in females and testosterone levels in males. Group A: primary hypogonadism; Group B: central hypogonadism; Group C: partial gonadal & central dysfunction; Group D: mild central and severe gonadal dysfunction. Criteria for classifying patients in each group according to inhibin B and FSH levels are described in “Results.” The grey bars represent the normal ranges. Among the 4 groups P < 0.0001 for the differences in FSH and INB, P < 0.001 for the differences in LH and P < 0.01 for AMH. Among the males, P < 0.0001, P < 0.03 and P < 0.01 respectively for INB, testosterone and AMH. Among the females, P < 0.001 for INB (ANOVA).