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Figure 3 | Reproductive Biology and Endocrinology

Figure 3

From: Phosphorylation of h1 Calponin by PKC epsilon may contribute to facilitate the contraction of uterine myometrium in mice during pregnancy and labor

Figure 3

The effect of PKC-ε specific activator (PSI-RACK) and inhibitor on the contraction of the mice myometrium strips at the day 19 during pregnant. A: typical recording of the contraction amplitude of myometrium strips was exposed to different dosage of PKC-ε specific activator (Psi-RACK) in the organ bath experiments. B: mean values of AUC (area of under a curve) were recorded in myometrium strips opposed to different dosage of PKC-ε specific activator (Psi-RACK) in the organ bath experiments. C: blots show the expression of calponin and h1-calponin in the myometrium strips opposed to PKC-ε activator or inhibitor. D: columns from the ratio of phosphorylated h1 calponin to total h1 calponin in the myometrium strips opposed to PKC-ε activator or inhibitor. (0: control, I: Psi-RACK (PKC-ε activator) 10-9 mol/L, II: epsilon-V1-2(PKC-ε inhibitor) 10-9 mol/L, III: Psi-RACK 10-9 mol/L + epsilon-V1-2 10-9 mol/L). h1 Cap: h1 calponin; p- h1 Cap: phosphorylated h1 calponin. *: P < 0.05, compared with control.

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