Table 4 Clinical and endocrine-metabolic parameters with different LH G1052A genotype and LHR new SNP genotype in PCOS patients
| Â | LH1052G/G (N=302) | LH1052G/A+A/A (N=13) | LHR wild type (N=246) | LHR mutated type (N=69) |
|---|---|---|---|---|
BMI(kg/m2) | 24.243.93 | 22.743.83 | 24.203.91 | 24.154.03 |
WHR | 0.830.07 | 0.810.05 | 0.830.07 | 0.820.06 |
Amenorrhea,n(%) | 276(91.39) | 11(84.62) | 223(90.65) | 65(94.20) |
PCO,n(%) | 282(93.37) | 11(84.62) | 227(92.28) | 66(95.65) |
LH(mIU/ml) | 9.236.44 | 5.714.07* | 8.856.47 | 9.966.06 |
FSH(mIU/ml) | 6.211.91 | 5.902.28 | 6.191.97 | 6.231.82 |
LH/FSH | 1.520.99 | 1.091.06 | 1.471.02 | 1.610.88 |
Testosterone ( nmol/L) | 1.801.10 | 1.911.04 | 1.791.07 | 1.861.22 |
A( nmol/L) | 13.665.59 | 13.764.59 | 13.675.50 | 13.635.78 |
Fasting glucose(mmol/L) | 4.920.63 | 5.321.54* | 4.930.73 | 4.980.60 |
Fasting insulin(uIU/ml) | 9.706.30 | 13.279.38 | 12.839.13 | 14.249.88 |
TG(mmol/L) | 1.561.01 | 1.260.49 | 1.550.97 | 1.551.07 |