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Table 1 Classification of OHSS symptoms[5] (adapted from Navot et al [9])

From: Predicting and preventing ovarian hyperstimulation syndrome (OHSS): the need for individualized not standardized treatment

OHSS stage Clinical features Laboratory features
Mild Abdominal distension/discomfort No important alterations
Mild nausea/vomiting
Diarrhea
Enlarged ovaries
Moderate Mild features + Elevated hematocrit (>41 %)
Ultrasonographic evidence of ascites Elevated WBC (>15000)
  Hypoproteinemia
Severe Mild and moderate features + Hemoconcentration (Hct >55 %)
Clinical evidence of ascites WBC >25000
Hydrothorax CrCl <50 mL/min
Severe dyspnea Cr >1.6
Oliguria/anuria Na+ <135 mEq/L
Intractable nausea/vomiting K+ >5 mEq/L
Tense ascites Elevated liver enzymes
Low blood/central venous pressure  
Rapid weight gain (>1 kg in 24 hours)  
Syncope  
Severe abdominal pain  
Venous thrombosis  
Critical Anuria/acute renal failure Worsening of findings
Arrhythmia
Thromboembolism
Pericardial effusion
Massive hydrothorax
Arterial thrombosis
Adult respiratory distress syndrome
Sepsis
  1. Cr = serum creatinine level; CrCl = creatinine clearance; WBC = white blood cell count.