Table 2 Frequencies of the epithelial expression levels of GPER (nuclear and cytoplasmic) and the classical sex hormone receptors in normal endometrium and endometriosis
Receptor | Expression level | Endometrium | Endometriosis | p-value |
|---|---|---|---|---|
GPER cyt | High | 0/30 | 30/60 (50%) | <0.001 |
| Â | Low | 30/30 (100%) | 30/60 (50%) | Â |
GPER nuc | High | 19/30 (63.3%) | 42/60 (70%) | 0.6 |
| Â | Low | 11/30 (36.7%) | 18/60 (30%) | Â |
ER-alpha | High | 28/30 (93.3%) | 57/63 (90.5%) | 0.7 |
| Â | Low | 2/30 (6.7%) | 6/63 (9.5%) | Â |
ER-beta | High | 3/30 (10%) | 35/65 (53.8%) | <0.001 |
| Â | Low | 27/30 (90%) | 30/65 (46.2%) | Â |
PR | High | 29/30 (96.7%) | 42/60 (70%) | 0.005 |
| Â | Low | 1/30 (3.3%) | 18/60 (30%) | Â |